Abstract
INTRODUCTION
Although e-cigarettes can be an effective form of nicotine substitution for adults attempting to quit smoking, their use among children and young people is a concern. Accurate data about this are needed to inform debates over policy and regulation in the UK and elsewhere.
METHODS
Using data from an online survey of 2613 youth aged 11–18 years, conducted by the market research company YouGov in March 2022, we present prevalence estimates of e-cigarette and tobacco use. We use logistic regression models to assess differences in e-cigarette use, tobacco use and use of disposable e-cigarettes across a range of covariates including age, sex, tobacco smoking status, social class, and country.
RESULTS
Among the 18.0% of those surveyed who reported ever having smoked a cigarette, 83.9% were not regular (at least once per week) smokers and 16.1% were (15.1% and 2.9% of the total sample, respectively). Among the 19.2% of those surveyed who had ever used an e-cigarette, 79.2% were not regular users, while 20.8% were (15.2% and 4.0% of the total sample, respectively). Regular e-cigarette use was more common than regular tobacco smoking (4.0% vs 2.9%). E-cigarette use was more common among those who also smoked tobacco, with 9.0% of never e-cigarette users ever smoking tobacco, compared with 89.4% of regular e-cigarette users. Both smoking and e-cigarette use were associated with increasing age and use by others within the home, but not with social class. Use of disposable e-cigarettes was reported by 53.8% of those who have ever used an e-cigarette, and more common among females than males.
CONCLUSIONS
Regular e-cigarette use is now more common than smoking in children and youth, though the majority of this is among those who have also smoked tobacco. Measures to reduce the appeal of both e-cigarettes and tobacco to children and young people are warranted.
Keywords: e-cigarettes, youth tobacco use, Great Britain
INTRODUCTION
The use of e-cigarettes as a tool for harm reduction among people with tobacco dependence has gained recent momentum in the UK, and in 2021 the Medicines and Healthcare Products Regulatory agency (MHRA) announced that it would facilitate the process for e-cigarettes to become licensed as medicinal products. This would allow them to be marketed explicitly as smoking cessation aids and prescribed in smoking cessation clinics and elsewhere1. Although UK youth smoking rates are at an all-time low2, there are growing concerns that e-cigarette use may be developing among tobacco-naive young people, particularly the suggestion that e-cigarette use within this population may act as a gateway to cigarette smoking. In the US, a 2018 report by the National Academies of Sciences, Engineering, and Medicine (NASEM) concluded that there was evidence for a causal effect of e-cigarette use on youth transition from non-smoker to ever smoker, while the Centers for Disease Control and Prevention (CDC) describe youth e-cigarette use as a serious public health concern3,4. Within the UK, a 2020 PHE report stated that the majority of youth never smokers had also never used an e-cigarette with only 0.8–1.3% of tobacco-naive youth reporting that they were current e-cigarette users, concluding with a statement that e-cigarette prevalence among the UK’s young people needs to be closely monitored5.
Given the importance of observing smoking and e-cigarette use within the younger population and the need for vigilance to track developments in the market, we report data from the 2022 ASH/YouGov Smoke-free GB-Youth survey on youth smoking and e-cigarette use.
METHODS
Data
Data came from the ASH/YouGov Smoke-free GB-Youth survey of 2613 youth aged 11–18 years, collected between 1 and 29 March 2022. Data were collected by YouGov, a public limited company, from an online panel recruited using proprietary software which is detailed elsewhere6. Participants are recruited to a main online panel and give sociodemographic information which is periodically updated. From this main online panel a method called Active Sampling assesses which members from the main panel are suitable for specific data collections, and this study is based on members contributing to the Smoke-free GB-Youth Survey7. The survey is designed to be representative of the population and survey weights are derived by YouGov in order to make the data representative across age, sex and region. Consent was provided by participants if they were aged ≥16 years, and by their parents if aged <16 years.
Measures
E-cigarette use was assessed using the question ‘Which one of the following is closest to describing your experience of e-cigarettes?’. We categorized this into never e-cigarette users (‘I have never used an e-cigarette’), non-regular e-cigarette users (‘I have only tried an e-cigarette once or twice’; ‘I used e-cigarettes in the past but no longer do’; ‘I use e-cigarettes more than once a month, but less than once a week’; ‘I use e-cigarettes sometimes, but no more than once a month’), and regular use (‘I use e-cigarettes more than once a week but not every day’; ‘I use e-cigarettes every day’). We also classified respondents who replied that they had never heard of e-cigarettes as never e-cigarette users. Tobacco use was assessed using the same categories. We present regression analyses for both regular use and ever use of both tobacco and e-cigarettes.
Participants who reported ever use of e-cigarettes were also asked about the order of product use. We report the percentage of cigarette smoking among those choosing to select ‘I tried smoking a real cigarette before I first tried using an e-cigarette’ compared with those who selected ‘I tried using an e-cigarette before I first tried smoking a real cigarette’. Ever e-cigarette users were also asked: ‘Have you ever used a disposable electronic cigarette (non-rechargeable)?’ which was classified as yes or no.
Other data included were age group (11–13, 14–15, 16–17, and 18 years), sex, social class [based on the Registrar General classification of occupations and classified as ABC1 (higher) vs C2DE (lower)], and country of Great Britain (England, Scotland, Wales). We assessed household use of e-cigarettes and tobacco from the questions: ‘Does anyone who currently lives in your home use an e-cigarette? (yes/no)’, and ‘Who in your family, if anyone, smokes tobacco cigarettes at the moment?’. For cigarette use in the family, we created a binary variable which categorized all of: ‘mother (or female carer)’, ‘father (or male carer)’, ‘brother or sister’, ‘grandparent’ and ‘other family member(s)’ as yes. We also assessed exposure to e-cigarette promotion using the question: ‘For the following question, by 'being promoted', we mean something that tries to increase interest in or demand for e-cigarettes. In which, if any, of the following places do you ever see e-cigarettes being promoted?’. Participants could select either none, or more than one response, and we categorized exposure as selecting at least one of billboards, shops, online, on buses, on TV, in newspapers/magazines, or ‘somewhere else’. We did not have data on exposure to tobacco advertising.
Statistical analysis
Descriptive statistics are presented after accounting for survey weighting. Logistic regression analyses assessed differences in ever and regular e-cigarette and tobacco use and use of disposable e-cigarettes among those who reported ever use of e-cigarettes. All these models were adjusted for the sociodemographic factors age, sex, country (England, Scotland, Wales) and social class. Models of e-cigarette use were also adjusted for reporting seeing e-cigarette promotion as well as e-cigarette use within the home. Models of tobacco smoking were adjusted for sociodemographic factors as well as family tobacco smoking. Analyses were performed in Stata 15.
RESULTS
The majority of participants lived in England (2281), with 206 in Scotland and 126 in Wales (Table 1). There were 1756 participants in higher social classes and 755 in lower social classes. There were 341 participants aged 18 years and the majority of participants (997) were aged 11–13 years.
Table 1.
Analytic sample, numbers weighted using survey weighting. Data from 2022 survey of youth aged 11–18 years in Great Britain
| Characteristics | n | % |
|---|---|---|
| Age (years) | ||
| 11–13 | 997 | 38.2 |
| 14–15 | 625 | 23.9 |
| 16–17 | 649 | 24.8 |
| 18 | 341 | 13.1 |
| Sex | ||
| Male | 1340 | 51.3 |
| Female | 1273 | 48.7 |
| Social class* | ||
| Higher | 1756 | 67.2 |
| Lower | 755 | 28.9 |
| Country | ||
| England | 2281 | 87.3 |
| Scotland | 206 | 7.9 |
| Wales | 126 | 4.8 |
| Overall | 2613 | 100 |
Defined by Registrar General’s classification of occupations and classified as ABC1 (higher) versus C2DE (lower).
Ever smoking tobacco was reported by 18.0% (417) of the sample; 83.9% (350) of these were non-regular smokers (absolute percentage 15.1%), and 16.1% (67) were regular smokers (absolute percentage 2.9%) (Table 2). Among the 19.2% (445) of those surveyed who had ever used an e-cigarette, 79.2% were not regular users, while 20.8% were (15.2% and 4.0% respectively). Regular e-cigarette use was more common than regular tobacco smoking (4.0% vs 2.9%). E-cigarette use was more common among those who also smoked tobacco, with 9.0% of never e-cigarette users ever smoking tobacco, compared with 89.4% of regular e-cigarette users.
Table 2.
E-cigarette use (%) by tobacco smoking status among youth aged 11–18 years in Great Britain, 2022 (N=2318)
| Characteristics | Never smoked tobacco % (n) | Non-regular tobacco smoker % (n) | Regular smoker % (n) | Ever smoked tobacco % (n) | Total % (n) |
|---|---|---|---|---|---|
| Never used e-cigarettes | 91.0 (1704) | 8.5 (159) | 0.5 (10) | 9.0 (169) | 80.8 (1873) |
| Non-regular e-cigarette user | 24.4 (86) | 57.9 (204) | 17.8 (63) | 75.65 (267) | 15.2 (352) |
| Regular e-cigarette user | 10.6 (10) | 41.2 (38) | 48.2 (45) | 89.4 (83) | 4.0 (93) |
| Ever e-cigarette user | 21.5 (96) | 54.4 (242) | 24.1 (107) | 19.2 (445) | |
| Total | 82.0 (1901) | 15.1 (350) | 2.9 (67) | 18.0 (417) | 100 (2318) |
Never: ‘I have never used an e-cigarette’. Non-regular: ‘I have only tried an e-cigarette once or twice’, ‘I used e-cigarettes in the past but no longer do’, ‘I use e-cigarettes more than once a month, but less than once a week’, and ‘I use e-cigarettes sometimes, but no more than once a month’. Regular: ‘I use e-cigarettes more than once a week but not every day’, and ‘I use e-cigarettes every day’. Respondents who said that they had never heard of e-cigarettes were also classified as never e-cigarette users.
Questions on ordering of product use were asked only of those who reported ever trying an e-cigarette. The majority of people who had ever used an e-cigarette had also tried smoking (65.0%; 368); 19.4% (110) reported that they used an e-cigarette before smoking a regular cigarette, and 45.6% (258) reported smoking a regular cigarette before using an e-cigarette. Being a regular smoker was more common among those who reported using tobacco before e-cigarettes than among those who used e-cigarettes first (20.2% vs 9.3%).
Differences in ever and regular use of e-cigarettes are shown in Table 3. Ever use was more common as age increased (p<0.001); participants aged 18 years were considerably more likely to report ever use than those aged 11–13 years (adjusted odds ratio, AOR=13.79; 95% CI: 8.91–21.35) (Figure 1). Ever use was more common among participants reporting regular e-cigarette use in their home (AOR=6.65; 95% CI: 5.08–8.70), although no differences were detected by social class or country. Associations were similar for regular use, with use more common among older participants and those reporting e-cigarette use inside the home (AOR=20.75; 95% CI: 11.86–36.28). Reporting exposure to e-cigarette promotion was linked to greater likelihood of ever use of e-cigarettes (AOR=1.61; 95% CI: 1.23–2.50) with a weaker association with regular e-cigarette use (AOR=1.52; 95% CI: 0.93–2.50).
Table 3.
Ever and regular use of e-cigarettes by selected characteristics among youth aged 11–18 years in Great Britain, 2022 (N=2003)
| Characteristics |
Ever use
|
Regular use
|
||
|---|---|---|---|---|
| AOR | 95% CI | AOR | 95% CI | |
| Gender | ||||
| Boys (Ref.) | 1 | 1 | ||
| Girls | 1.11 | 0.87–1.41 | 1.25 | 0.81–1.92 |
| Age (years) | ||||
| 11–13 (Ref.) | 1 | 1 | ||
| 14–15 | 3.23 | 2.09–4.99 | 2.80 | 1.00–7.84 |
| 16–17 | 7.93 | 5.23–12.00 | 9.54 | 3.65–24.94 |
| 18 | 13.79 | 8.91–21.35 | 10.68 | 4.08–27.93 |
| Country | ||||
| England (Ref.) | 1 | 1 | ||
| Scotland | 1.23 | 0.85–1.78 | 1.02 | 0.52–2.02 |
| Wales | 0.52 | 0.25–1.10 | 0.40 | 0.08–1.98 |
| Social class | ||||
| Higher* (Ref.) | 1 | 1 | ||
| Lower | 0.93 | 0.72–1.20 | 0.71 | 0.44 – 1.13 |
| Awareness of e-cigarettes | ||||
| Has not seen e-cigarettes promoted** | 1 | 1 | ||
| Has seen e-cigarettes promoted | 1.61 | 1.23–2.09 | 1.52 | 0.93–2.50 |
| E-cigarette use | ||||
| No e-cigarette use in home (Ref.) | 1 | 1 | ||
| E-cigarette use in home | 6.65 | 5.08–8.70 | 20.75 | 11.86–36.28 |
AOR: adjusted odds ratio.
Defined by Registrar General’s classification of occupations and classified as ABC1 (higher) versus C2DE (lower).
In at least one of billboards, shops, online, on buses, on TV, in newspapers/magazines, or ‘somewhere else’.
Figure 1.
E-cigarette use among those aged 11–18 years, in Great Britain, 2022
Differences in ever and regular tobacco smoking are shown in Table 4. These present a similar picture to that for e-cigarette use. Ever use was more common among older participants (e.g. AOR for youth aged 18 years vs youth aged 11–13 years = 10.79; 95% CI: 7.43–15.68) as well as those with cigarette smoking in the family (AOR=2.42; 95% CI: 1.93–3.04). Regular smoking was more common among older participants (p<0.001) and those reporting cigarette smoking in the family (AOR=3.87; 95% CI: 2.34–6.41). We did not detect differences by sex or social class for either ever or regular tobacco smoking.
Table 4.
Ever and regular tobacco smoking by selected characteristics among youth aged 11–18 years in Great Britain, 2022 (N=2474)
| Characteristics |
Ever use
|
Regular use
|
||
|---|---|---|---|---|
| AOR | 95% CI | AOR | 95% CI | |
| Gender | ||||
| Boys (Ref.) | 1 | 1 | ||
| Girls | 0.92 | 0.74–1.15 | 0.84 | 0.51–1.39 |
| Age (years) | ||||
| 11–13 (Ref.) | 1 | 1 | ||
| 14–15 | 2.42 | 1.62–3.61 | 1.28 | 0.47–3.51 |
| 16–17 | 6.50 | 4.53–9.34 | 3.80 | 1.62–8.89 |
| 18 | 10.79 | 7.43–15.68 | 5.81 | 2.47–13.65 |
| Country | ||||
| England (Ref.) | 1 | 1 | ||
| Scotland | 1.18 | 0.84–1.65 | 1.33 | 0.67–2.63 |
| Wales | 0.51 | 0.27–0.97 | 0.61 | 0.19–1.96 |
| Social class | ||||
| Higher* (Ref.) | 1 | 1 | ||
| Lower | 1.01 | 0.79–1.27 | 1.11 | 0.67–1.85 |
| Cigarette smoking in family | ||||
| No cigarette smoking in family (Ref.) | 1 | 1 | ||
| Cigarette smoking in family | 2.42 | 1.93–3.04 | 3.87 | 2.34–6.41 |
AOR: adjusted odds ratio.
Defined by Registrar General’s classification of occupations and classified as ABC1 (higher) versus. C2DE (lower).
Differences in use of disposable e-cigarettes among ever e-cigarette users are shown in Table 5. Use of disposable products was more common among females (AOR=1.69; 95% CI: 1.14–2.51), aged 18 years (AOR=2.78; 95% CI: 1.17–6.61), and those reporting e-cigarette use in the home (AOR=2.60; 95% CI: 1.74–3.88).
Table 5.
Use of disposable e-cigarettes among ever e-cigarette users aged 11–18 years in Great Britain, 2022 (N=513)
| Characteristics | % | AOR | 95% CI |
|---|---|---|---|
| Gender | |||
| Boys (Ref.) | 50.9 | 1 | |
| Girls | 59.3 | 1.69 | 1.14–2.51 |
| Age (years) | |||
| 11–13 (Ref.) | 41.1 | 1 | |
| 14–15 | 45.7 | 1.29 | 0.53–3.14 |
| 16–17 | 59.6 | 2.33 | 0.99–5.49 |
| 18 | 62.5 | 2.78 | 1.17–6.61 |
| Country | |||
| England (Ref.) | 54.9 | 1 | |
| Scotland | 56.7 | 0.80 | 0.45–1.41 |
| Wales | 60.3 | 1.79 | 0.38–8.4 |
| Social class | |||
| Higher* (Ref.) | 53.3 | 1 | |
| Lower | 58.8 | 1.24 | 0.82–1.89 |
| Awareness of e-cigarettes | |||
| Has not seen e-cigarettes promoted** (Ref.) | 54.8 | 1 | |
| Has seen e-cigarettes promoted | 56.6 | 1.22 | 0.77–1.95 |
| E-cigarette use | |||
| No e-cigarette use in home (Ref.) | 45.6 | 1 | |
| E-cigarette use in home | 66.3 | 2.60 | 1.74–3.88 |
AOR: adjusted odds ratio.
Defined by Registrar General’s classification of occupations and classified as ABC1 (higher) versus C2DE (lower).
In at least one of billboards, shops, online, on buses, on TV, in newspapers/magazines, or ‘somewhere else’.
DISCUSSION
Youth tobacco smoking and e-cigarette usage remained low in 2022, with e-cigarette usage in this population now slightly higher than regular tobacco smoking. Compared to data from 2020–2021, the low smoking prevalence is unchanged and regular e-cigarette use is also similar (4.0% vs 4.3%)8. Most e-cigarette users reported that they have experimented with or are regular tobacco users alongside their e-cigarette use.
Despite youth smoking rates being at an all-time low, increases in e-cigarette use in those without previous tobacco smoking raises the concern about a potential gateway effect of e-cigarette use to tobacco smoking, which is concerning. Although there are likely to be common susceptibility factors for both tobacco and e-cigarette use (family and peer-group use, social class, genetic susceptibility etc.), there is a need for regulation and enforcement to avoid uptake of e-cigarette use among children. This is necessary both to reduce the risk of potential harms from short- or long-term exposure to vaping, and to avoid any risk of transitioning to smoking. As adult smoking rates decrease, and rates of adult e-cigarette use increase, it is to be expected that patterns of use among young people will reflect this. Thus, in 2018, ASH Smoke-free survey data highlighted that 18.3% of young ever tobacco smokers reported having tried e-cigarettes before they smoked a conventional cigarette for the first time8; the same survey 3 years later, this figure had increased to 29.3% of youths trying e-cigarettes before smoking tobacco8. Data from different settings are similar. For example, a 2020 longitudinal analysis of e-cigarette and smoking use in the US concluded that adolescents who reported current exclusive use of e-cigarettes were five times more likely to be tobacco smokers one year later than non-current e-cigarette users9. A meta-analysis of three longitudinal studies from the UK has identified that ever e-cigarette users were six times more likely to take up tobacco smoking than never e-cigarette users, and there are similar findings from studies across Europe and North America10,11.
The present findings indicate that current laws limiting child access to tobacco and e-cigarettes are not adequately enforced and underscore recent recommendations for increased investment in local smoke-free enforcement actions12. Current regulation in the UK prohibits the sale of nicotine containing e-cigarettes to those aged <18 years13. While we did not assess whether e-cigarettes used by study respondents contained nicotine, previous analyses of these data found that 76% of participants reported that their e-cigarettes always or sometimes contained nicotine14. This has also been demonstrated across secondary school children (aged 13–18 years) in New Zealand whereby 80% of regular users and 90% of weekly users of e-cigarettes, reported using nicotine containing devices15. The introduction of ‘pod’ devices onto the market in 2015, which typically do not offer nicotine-free options, is one possible cause of youth using nicotine-containing e-cigarettes16,17. Students who use popular pod devices such as JUUL may not be aware of the amount of nicotine they are consuming. For example, a 2019 US survey study of high school students reported poor understanding of the levels of nicotine contained in JUUL in addition to more than one-third of participants being unaware whether a JUUL was an e-cigarette or not18.
Age is also a significant factor regarding e-cigarette and smoking behavior. As demonstrated in previous8 and by our current survey data, 18-year-olds are significantly more likely to report ever smoking and e-cigarette use compared with younger age groups. We found that use of e-cigarettes by others within the home was associated with e-cigarette use among youth, and the same was true for tobacco smoking. This is not surprising and is a well-known risk factor for smoking behavior in young people, observed in a range of settings19-22. We also found that reporting exposure to promotion of e-cigarettes was linked to ever use of these products, which is a concern. A 2018 RCT explored the effect of advertisements designed to attract youth on tobacco, and e-cigarette attitudes and susceptibility among 417 non-smoking adolescents23. It was found that participants exposed to the advertisements designed to attract youth were almost seven times more likely to select e-cigarettes in tests of choice, than the control group. This study also found that susceptibility to e-cigarettes increased even among participants exposed to advertisements designed to have low levels of appeal to youth23. Similarly, a recent systematic review found that pod-based e-cigarettes have been targeting young people with social media advertising, with minimal information on the health risks and usage as a smoking cessation tool compared to other e-cigarette devices24. These findings underscore the need to strengthen enforcement of the rules on advertising, promotion and enforcement, and review whether they need further strengthening, particularly for popular pod-based devices and social media marketing spaces.
Disposable e-cigarette use in the US and UK is growing, recent data from a cross-sectional survey of adults in Great Britain concluded that use of disposable e-cigarettes grew significantly in 2022, predominantly by those aged 18 years25. We found that among ever e-cigarette users, use of disposables was reported by more than half of respondents, more commonly among females and youth aged 18 years. More research is needed to understand the reasons and risk factors for use of disposable e-cigarettes among younger populations.
Limitations
Limitations of the current study include the cross-sectional survey study design, thus we cannot infer causality or explain trajectories of tobacco smoking, e-cigarette use and quitting of products. It is plausible that some e-cigarette use in this population is among tobacco smokers attempting to quit, or may replace trying smoking, and further research into these issues is needed. Importantly, the study sample was designed to be representative of the Great Britain population and these results add to the ongoing surveillance of smoking and e-cigarette use among the UK’s younger population, which is vital for understanding and informing tobacco control policy. There may also be some confusion around what does and does not constitute an e-cigarette. The survey, however, did clarify to participants that e-cigarettes are ‘sometimes called vapes, shisha pens or electronic cigarettes’. The study was conducted in Great Britain, thus these results may not necessarily be extrapolated to other settings, and the fact that we did not assess the presence or absence of nicotine in the e-cigarettes used, nor the specific ingredients included.
CONCLUSIONS
Rates of e-cigarette use among young people are now higher than smoking, though the vast majority of those who are regular e-cigarette users also smoke or have done so in the past. Measures are needed to reduce the appeal of these devices to young people as well as enforcement of laws to prevent illegal sales and marketing.
ACKNOWLEDGEMENTS
The Department of Primary Care & Public Health at Imperial College London is grateful for support from the NW London NIHR Applied Research Collaboration and the NIHR Imperial Biomedical Research Centre.
CONFLICTS OF INTEREST
The authors have each completed and submitted an ICMJE form for disclosure of potential conflicts of interest. The authors declare that they have no competing interests, financial or otherwise, related to the current work. N.S. Hopkinson reports that in the past 36 months he is the Medical Director at Asthma and Lung UK and Chair at Action on Smoking and Health (UK). A.A. Laverty reports that in the past 36 months received consulting fees from the World Health Organization to contribute to a systematic review on health effects of Electronic Nicotine Delivery Systems and a Trustee at Action on Smoking in Lung Health.
FUNDING
PW is funded by RM Partners, West London Cancer Alliance, hosted by The Royal Marsden NHS Foundation Trust and Royal Brompton and Harefield Hospitals Charities. The ASH/YouGov Smoke-free GB-Youth survey is funded by the British Heart Foundation, Cancer Research UK, and the Department of Health and Social Care. The funders had no input into data analysis or the writing of this manuscript.
ETHICAL APPROVAL AND INFORMED CONSENT
Ethical approval was not required as data came from the ASH/YouGov Smoke-free GB-Youth survey. Consent was provided by participants if they were aged ≥16 years, and by their parents if the participants were <16 years.
DATA AVAILABILITY
The data supporting this research are available from the authors on reasonable request.
AUTHORS’ CONTRIBUTIONS
AAL, HC, DA, LB and NSH designed the study. AAL analyzed the data and PJW produced the first draft to which all authors contributed. All authors have reviewed and approved the final version. AAL is the guarantor.
PROVENANCE AND PEER REVIEW
Not commissioned; externally peer reviewed.
REFERENCES
- 1.UK Government MHRA publishes clear guidance to support bringing e-cigarettes to market as licensed therapies. Accessed October 10, 2022. https://www.gov.uk/government/news/mhra-publishes-clear-guidance-to-support-bringing-e-cigarettes-to-market-as-licensed-therapies.
- 2.UK National Health Service Digital Part 4: Smoking patterns among young people. Accessed October 10, 2022. https://digital.nhs.uk/data-and-information/publications/statistical/statistics-on-smoking/statistics-on-smoking-england-2019/part-4-smoking-patterns-in-children-copy#:~:text=Smoking%20prevalence%20among%20young%20people,-Smoking%20prevalence%2C%20by&text=6%25%20of%20pupils%20were%20current,3%25%20were%20regular2%20smokers.&text=Similar%20proportions%20of%20boys%20and,7%25%20of%2015%20year%20olds.
- 3.National Academies . Public Health Consequences of E-Cigarettes. National Academies; 2018. Accessed October 10, 2022. https://nap.nationalacademies.org/resource/24952/012318ecigaretteConclusionsbyEvidence.pdf. [PubMed] [Google Scholar]
- 4.Centers for Disease Control and Prevention Youth E-Cigarette Use Remains Serious Public Health Concern Amid COVID-19 Pandemic. Accessed October 10, 2022. https://www.cdc.gov/media/releases/2021/p0930-e-cigarette.html#:~:text=A%20study%20released%20today%20(attached,those%20youth%20using%20flavored%20e%2D.
- 5.Public Health England . Vaping in England: 2021 evidence update summary. Public Health England; 2021. Accessed October 10, 2022. https://www.gov.uk/government/publications/vaping-in-england-evidence-update-february-2021/vaping-in-england-2021-evidence-update-summary. [Google Scholar]
- 6.Eastwood B, Dockrell MJ, Arnott D, et al. Electronic cigarette use in young people in Great Britain 2013-2014. Public Health. 2015;129(9):1150–1156. doi: 10.1016/j.puhe.2015.07.009. [DOI] [PubMed] [Google Scholar]
- 7.YouGov Panel Methodology. Accessed October 10, 2022. https://yougov.co.uk/about/panel-methodology/#/accuracy.
- 8.Action on Smoking and Health Use of e-cigarettes among young people in Great Britain. 2021. Jun, Accessed October 10, 2022. https://ash.org.uk/wp-content/uploads/2021/07/Use-of-e-cigarettes-among-young-people-in-Great-Britain-2021.pdf.
- 9.Osibogun O, Bursac Z, Maziak W. E-Cigarette Use and Regular Cigarette Smoking Among Youth: Population Assessment of Tobacco and Health Study (2013-2016) Am J Prev Med. 2020;58(5):657–665. doi: 10.1016/j.amepre.2020.01.003. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 10.Aladeokin A, Haighton C. Is adolescent e-cigarette use associated with smoking in the United Kingdom?: A systematic review with meta-analysis. Tob Prev Cessat. 2019;5(April) doi: 10.18332/tpc/108553. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 11.O’Brien D, Long J, Quigley J, Lee C, McCarthy A, Kavanagh P. Association between electronic cigarette use and tobacco cigarette smoking initiation in adolescents: a systematic review and meta-analysis. BMC Public Health. 2021;21(1):1–10. doi: 10.1186/s12889-021-10935-1. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 12.U.K. Office for Health Improvement and Disparities The Khan review: making smoking obsolete. 2022. Jun 9, Updated August 25, 2022. Accessed October 10, 2022. https://www.gov.uk/government/publications/the-khan-review-making-smoking-obsolete.
- 13.UK Government . The Nicotine Inhaling Products (Age of Sale and Proxy Purchasing) Regulations. Government of the United Kingdom; 2015. Accessed October 10, 2022. https://www.legislation.gov.uk/ukdsi/2015/9780111130568#:~:text=These%20Regulations%2C%20made%20under%20Part,a%20person%20aged%20under%2018. [Google Scholar]
- 14.Action on Smoking and Health . Use of e-cigarettes (vapes) among young people in Great Britain 2022. Action on Smoking and Health; 2022. Accessed October 10, 2022. https://ash.org.uk/wp-content/uploads/2022/07/Use-of-e-cigarettes-among-young-people-in-Great-Britain-2022.pdf. [Google Scholar]
- 15.Ball J, Fleming T, Drayton B, Sutcliffe K, Lewycka S, Clark TC. New Zealand Youth19 survey: vaping has wider appeal than smoking in secondary school students, and most use nicotine-containing e-cigarettes. Aust N Z J Public Health. 2021;45(6):546–553. doi: 10.1111/1753-6405.13169. [DOI] [PubMed] [Google Scholar]
- 16.Goniewicz ML, Boykan R, Messina CR, Eliscu A, Tolentino J. High exposure to nicotine among adolescents who use Juul and other vape pod systems (‘pods’) Tob Control. 2019;28(6):676–677. doi: 10.1136/tobaccocontrol-2018-054565. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 17.Boykan R, Goniewicz ML, Messina CR. Evidence of Nicotine Dependence in Adolescents Who Use Juul and Similar Pod Devices. Int J Environ Res Public Health. 2019;16(12):2135. doi: 10.3390/ijerph16122135. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 18.Morean ME, Bold KW, Kong G, et al. Adolescents’ awareness of the nicotine strength and e-cigarette status of JUUL e-cigarettes. Drug Alcohol Depend. 2019;204:107512. doi: 10.1016/j.drugalcdep.2019.05.032. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 19.Hanewinkel R, Isensee B. Risk factors for e-cigarette, conventional cigarette, and dual use in German adolescents: a cohort study. Prev Med. 2015;74:59–62. doi: 10.1016/j.ypmed.2015.03.006. [DOI] [PubMed] [Google Scholar]
- 20.Laverty AA, Filippidis FT, Taylor-Robinson D, Millett C, Bush A, Hopkinson NS. Smoking uptake in UK children: analysis of the UK Millennium Cohort Study. Thorax. 2019;74(6):607–610. doi: 10.1136/thoraxjnl-2018-212254. [DOI] [PubMed] [Google Scholar]
- 21.Leonardi-Bee J, Jere ML, Britton J. Exposure to parental and sibling smoking and the risk of smoking uptake in childhood and adolescence: a systematic review and meta-analysis. Thorax. 2011;66(10):847–855. doi: 10.1136/thx.2010.153379. [DOI] [PubMed] [Google Scholar]
- 22.Vrinten C, Parnham JC, Filippidis FT, Hopkinson NS, Laverty AA. Risk factors for adolescent smoking uptake: Analysis of prospective data from the UK Millennium Cohort Study. Tob Induc Dis. 2022;20(October) doi: 10.18332/tid/152321. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 23.Padon AA, Lochbuehler K, Maloney EK, Cappella JN. A Randomized Trial of the Effect of Youth Appealing E-Cigarette Advertising on Susceptibility to Use E-Cigarettes Among Youth. Nicotine Tob Res. 2018;20(8):954–961. doi: 10.1093/ntr/ntx155. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 24.Lee SJ, Rees VW, Yossefy N, Emmons KM, Tan ASL. Youth and Young Adult Use of Pod-Based Electronic Cigarettes From 2015 to 2019: A Systematic Review. JAMA Pediatr. 2020;174(7):714–720. doi: 10.1001/jamapediatrics.2020.0259. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 25.Tattan-Birch H, Jackson SE, Kock L, Dockrell M, Brown J. Rapid growth in disposable e-cigarette vaping among young adults in Great Britain from 2021 to 2022: a repeat cross-sectional survey. Addiction. 2022 doi: 10.1111/add.16044. [DOI] [PMC free article] [PubMed] [Google Scholar]
Associated Data
This section collects any data citations, data availability statements, or supplementary materials included in this article.
Data Availability Statement
The data supporting this research are available from the authors on reasonable request.

