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. 2023 Jan 6;12(2):488. doi: 10.3390/jcm12020488

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Impact of SARS-CoV-2 infection on cardiovascular system in older adults. Entry of SARS-CoV-2 into host cells (ciliated nasal epithelium; cardiomyocytes and endothelial cells) is mediated by angiotensin-converting enzyme 2 (ACE2) receptor. Main cardiovascular clinical alterations include myocardial injury, myocarditis, acute coronary syndrome, cardiac arrhythmia and thromboembolism. Elevation of D-dimers or prothrombin time, factors involved in blood clotting, are hallmarks of SARS-CoV-2 virus infection. Therapies against SARS-CoV-2 are indicated.