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Immune state in elderly people and how SARS-CoV-2 infection affects immune system cells and soluble factors. (A) Several agents are involved in the physiological development of immunosenescence and inflammaging in elderly people. (B) A description of the different alterations that take place in elderly people after SARS-CoV-2 infection is shown. Antagonists of IL-6 and IL-1 and inhibitors of the JAK-STAT pathway are noted.
