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The effects of HLE on Aβ plaque in the hippocampus, cortex and femurs. (A) Congo red-positive plaque in the hippocampus, cortex or femurs of APP/PS1 mice; (B–D) quantitative analysis of amount of Aβ (n = 3). (** p < 0.01, *** p < 0.001, compared with the CON group; # p < 0.05, ## p < 0.01, ### p < 0.001 compared with the APP/PS1 group.)
