Table 1.
Baseline characteristics of the 179 patients awaiting LT and treated for HCV.
| Overall n = 179 (%) |
Decompensated Cirrhosis n = 75 (%) |
HCC n = 104 (%) |
|
|---|---|---|---|
| Male | 145 (81) | 57 (76.0) | 88 (84.6) |
| Age (years) Median (IQR) |
54 (51; 59) | 53 (49; 57) | 54.5 (52; 60) |
| BMI (kg/m2) Median (IQR) |
25.3 (22.6; 28) |
25.2 (22.8; 28) |
25.3 (22.2; 28) |
| Diabetes Mellitus | 48 (27.4) | 25 (34.3) | 23 (22.6) |
| Arterial hypertension | 44 (25.1) | 13 (17.8) | 31 (30.4) |
| Alcohol consumption | 39 (22.2) | 14 (18.9) | 25 (24.5) |
| Dyslipidemia | 8 (4.6) | 2 (2.7) | 6 (5.9) |
| Ascites None Controlled Refractory |
120 (67) 35 (19.6) 24 (13.4) |
33 (44) 25 (33.3) 17 (22.7) |
87 (83.7) 10 (9.6) 7 (6.7) |
| Hepatic encephalopathy None Grade I-II |
148 (82.7) 31 (17.3) |
50 (66.7) 25 (33.3) |
98 (94.2) 6 (5.8) |
| Total bilirubin(μmol/L) Median (IQR) |
29.8 (16; 48) |
41 (25.3; 62) |
19 (12; 35) |
| INR Median (IQR) |
1.2 (1.1; 1.5) |
1.5 (1.3; 1.8) |
1.2 (1.1; 1.2) |
| Albumin (g/L) Median (IQR) |
33.1 (29; 37.6) |
30 (26; 35.9) |
35.3 (31; 38.7) |
| MELD baseline Median (IQR) |
11 (8; 15) |
14 (11; 18) |
9 (7; 12) |
| Child–Pugh class at baseline A B C |
83 (48) 51(29.5) 39 (22.5) |
15 (20) 30 (40) 30 (40) |
68 (69.4) 21 (21.4) 9 (9.2) |
| SVR rate | 151 (84.4) | 69 (92) | 82 (78.9) |
| Liver transplant recipients | 121 (67.6) | 39 (52) | 82 (78.9) |
LT: liver transplantation; HCV: hepatitis C virus; HCC: hepatocellular carcinoma; BMI: body mass index; INR: international normalized ratio; MELD: Model for End-Stage Liver Disease; SVR: sustained virological response.