. 2023 Jan 1;11(1):48. doi: 10.3390/toxics11010048

Table 3.

Effect of DIOS on GNT-induced renal oxidative stress.

Groups	MDA	TAC	SOD
Control	44.50 $\pm$ 4.472	79.58 $\pm$ 8.695	42.68 $\pm$ 4.377
GNT	190.2 $\pm$ 13.040 ^a	31.12 $\pm$ 4.481 ^a	15.51 $\pm$ 1.350 ^a
GNT + DIOS	84.88 $\pm$ 9.566 ^a,b	51.20 $\pm$ 3.913 ^a,b	33.45 $\pm$ 2.931 ^a,b
DIOS	50.91 $\pm$ 9.671 ^b,c	70.82 $\pm$ 2.971 ^b,c	44.37 $\pm$ 3.258 ^b,c

The values designate the mean ± SD (n = 6). a: statistically significant from the control group, b: statistically significant from the GNT group, c: statistically significant from the GNT + DIOS group, p < 0.05 determined with one-way ANOVA tailed by Tukey’s multiple comparisons test. Abbreviations: GNT, gentamicin; MDA, malondialdehyde; DIOS, diosmin; SOD, superoxide dismutase; TAC, total antioxidant capacity.