Figure 3.

Multitasking of Candida spp. extracellular proteases in relation to the host immune cells. The figure was partly generated using Servier Medical Art, provided by Servier, licensed under a Creative Commons Attribution 3.0 unported license. ASC—apoptosis-associated speck-like protein containing a CARD, DC—dendritic cells, IL—interleukin, NET—neutrophil extracellular traps, NLRP3—intracellular NOD-like receptor 3, PAR2—proteinase-activated receptor 2, PC—pro-caspase-1, ROS—reactive oxygen species, Sap—secreted aspartyl proteinases, TNF-α—tumor necrosis factor α, MIP-2—macrophage inflammatory protein 2.