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. 2023 Jan 15;12(2):692. doi: 10.3390/jcm12020692

Table 1.

Characteristics of the study group for the total population and by the COVID-19 pandemic.

Variable Entire Study Group
N (%)
Before the Pandemic
N (%)
During the Pandemic
N (%)
Size Effect p ^
Sex Female 15,743 (78.2) 7887 (77.4) 7856 (78.9) 6.69 * 0.010
Male 4396 (21.8) 2300 (22.6) 2096 (21.1)
Age M ± SD 22.6 ± 3.6 22.4 ± 3.0 22.7 ± 4.1 0.083 # <0.001
Year of study I 5504 (27.3) 2180 (21.4) 3324 (33.4) 458.52 * <0.001
II 3600 (17.9) 2106 (20.7) 1494 (15.0)
III 3761 (18.7) 2173 (21.4) 1588 (16.0)
IV 3119 (15.5) 1624 (15.9) 1495 (15.0)
V 2885 (14.3) 1530 (15.0) 1355 (13.6)
VI 1270 (6.3) 574 (5.6) 696 (7.0)
University profile Medical 4518 (22.4) 2578 (25.3) 1940 (19.5) 97.73 * <0.001
Non-medical 15,621 (77.6) 7609 (74.7) 8012 (80.5)
HDI Very high 18,206 (90.4) 9432 (92.6) 8774 (88.2) 146.77 * <0.001
High 785 (3.9) 364 (3.6) 421 (4.2)
Medium 1000 (5.0) 329 (3.2) 671 (6.7)
Low 148 (0.7) 62 (0.6) 86 (0.9)
GDP per capita High 17,716 (87.9) 9252 (90.8) 8464 (85.0) 175.27 * <0.001
Upper-middle 1059 (5.3) 455 (4.5) 604 (6.1)
Lower-middle 973 (4.9) 348 (3.4) 625 (6.3)
Low 391 (1.9) 259 (2.6) 132 (1.3)
COVID-19 pandemic announcement Before the pandemic 10,187 (50.6) --- ---- --- ---
During the pandemic 9952 (49.4) --- ---
Place of study Europe 17,954 (89.1) 9372 (92.1) 8582 (86.2) 220.82 * <0.001
North America 147 (0.7) 65 (0.6) 82 (0.8)
South America 173 (0.9) 65 (0.6) 108 (1.1)
Asia 1425 (7.1) 474 (4.7) 951 (9.6)
Africa 390 (1.9) 167 (1.6) 223 (2.2)
Australia 50 (0.3) 35 (0.3) 15 (0.2)
Alcohol Yes 16,517 (82.0) 8833 (86.8) 7684 (77.1) 317.47 * <0.001
No 3622 (18.0) 1345 (13.2) 2277 (22.9)
Cannabinoids Yes 2731 (13.6) 1449 (14.2) 1282 (12.9) 8.01 * 0.004
No 17,408 (86.4) 8729 (12.9) 8679 (87.1)
Psychostimulants Yes 729 (3.6) 432 (4.2) 297 (3.0) 23.01 * <0.001
No 19,410 (96.4) 9746 (95.8) 9664 (97.0)
Sedatives Yes 2522 (22.6) 1183 (11.6) 1339 (13.4) 15.21 * <0.001
No 17,617 (87.4) 8995 (88.4) 8622 (86.6)

M—mean; SD—standard deviation; HDI—Human Development Index; GDP—Gross domestic product; * Chi2; # Cohen’s d; ^ comparison of distribution in relation to the COVID-19 pandemic. Statistically significant values are in bold with the significance level set at p < 0.05.