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Molecular structure of CD96. CD96 has three Ig domains. The domain of hCD96 subtype1 is V, V, and C; the domain of hCD96 subtype2 and mCD96 is V, I/C, and C. Where the c on the domain loop refers to cysteine. N-glycosylation sites indicated by attached black circles; serines and threonines in the putative O-glycosylated region are indicated by attached open circles.
