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. 2023 Jan 16;24(2):1803. doi: 10.3390/ijms24021803

Table 2.

The unfolding volumes and temperatures of DNA GQs, and the corresponding experi-mental conditions.

Name Cation Cation Conc. ΔV
(cm3/mol)		 Tm at 1bar (°C) Oligomer Conc. (μM) N Topology pH Buffer Ref
TBA K+ 100 mM −54.6 ± 4.2 52.6 ± 3.4 40 15 AP - TRIS 30 mM [26]
Htel22 Na+ 100 mM −38.4 ± 10.1 54.6 ± 0.9 20 22 AP 7.4 TRIS 10 mM [66]
Htel22 Na+ 2 0mM −68 ± 2 1 39.6 ± 0.7 1 10–300 4 22 AP 7.0 Na phosph 10mM [46]
Htel22 Na+ 50 mM −60 ± 2 1 47.9 ± 0.7 1 10–300 4 22 AP 7.0 Na phosph 10mM [46]
Htel22 Na+ 100 mM −56 ± 2 1 54.9 ± 0.6 1 10–300 4 22 AP 7.0 Na phosph 10mM [46]
Htel22 K+ 100 mM −42.7 ± 6.7 64.6 ± 2.2 20 22 H 7.4 Tris 10 mM [66]
c-MYC K+ 170 mM −16.9 ± 1.8 83.4 ± 1.3 2 22 P 7.4 K-phosph 100 mM [62]
KIT K+ 170 mM −6.2 ± 0.9 58.5 ± 0.4 2 22 P 7.4 K-phosph 100 mM [62]
VEGF K+ 170 mM −18.1 ± 4.6 78.8 ± 1.1 2 24 P 7.4 K-phosph 100 mM [62]
Htel26 K+ 20 mM −69 ± 7 2 NA 300 26 H 7.0 tetrabutylammonium
phosphate		 [63]
c-MYC K+ 0.1 mM −30 ± 4 59.1 25 22 P 7.0 Cs-phosp 10 mM [67]
HepB1 K+ 140 mM 17.8 ± 3.8 NA 1 27 NA 7.4 3 K-phosp/TRIS [14]
HepB1 K+ 100 mM 16.1 ± 2.0 53.8 2400 27 NA 7.4 Bis-TRIS 100 mM [14]
HepB2 K+ 140 mM −3.7 ± 0.6 51.9 1 25 NA 7.4 3 K-phosp/TRIS [14]
HepB3 K+ 140 mM 2.0 ± 1.1 41.4 1 23 NA 7.4 3 K-phosp/TRIS [14]
TBA (+PEG) K+ 100 mM −13.1 ± 1.0 60.6 ± 3.2 40 15 AP 7.0 TRIS 30 mM [26]
Htel22 K+ 170 mM −19 ± 3 63 10 21 H 7.4 K-phosph 100 mM [51]
Htel22 K+ 200 mM 6.4 ± 1 NA 9400 21 P? 7.4 Bis-TRIS 200 mM [51]
TG4T Na+ 1 M 1.5 ± 2.3 68.9 100 4 × 7 P 7.5 TRIS 10 mM [65]
Pu22T12T13 K+ 2 mM −38 ± 10 71.8 100 22 P 7.0 tetrabutylammonium
phosphate		 [65]

1 Weighted average of the published values obtained from different experimental techniques. 2 K+ induced volume change at 25 °C. 3 Ph7.4 K-phosphate buffer was used for determination of the Tm at atmospheric pressure, the pH dependence was ruled out by a 3D fitting. 4 Depending on the used experimental techniques.