Figure 2.

Schematic representative of recently developed antibody-based drug in different neurological diseases. Antibody-based drugs exert their therapeutic effects through a variety of mechanisms. Some antibodies block the function of the membrane receptors. Others target specific complement proteins for cell depletion. Finally, antibody-based drugs can target specific effector molecules from interacting with their ligands. Immunogens include IL-6L/R, interleukin 6 ligand/receptor; CGRPL/R: calcitonin gene-related peptide ligand/receptor; CD19/20: cluster of differentiation 19/20; C5: complement factor 5 protein.