Table 1.
Compound | Source | Effect | LD50, μg/kg | Mr
(Relative Molecular Mass) |
---|---|---|---|---|
Tubocurarine | Chondrodendron spp. | Myorelaxant | 130 (mouse, i.v.) [4] | 609.7 |
Ouabain | Strophanthus spp. | Cardioactive glycoside | 110 (cat, i.v.) [5] | 584.7 |
Antiarin | Antiaris toxicaria | Cardioactive glycoside | 120 (mouse, i.v.) [6] | 566.6 |
Aconitine | Aconitum spp. | Interaction with Na-channels | 110 (rat, i.v.) [7] | 645.7 |
Botulinum toxin | Clostridium botulinum | Acetylcholine blockade | 0.001 (mouse, i.v.) [8] | 150 000 |
Ricin | Ricinus communis | Inhibition of protein synthesis | 3 (mouse, i.p.) [9] | 62 000 |
Saxitoxin (STX) | Dinoflagellata | Blockade of Na-channels | 10 (mouse, i.p.) [10] | 299.1 |