Figure 4.

Competition of four recombinant sea anemone peptides with [¹²⁵I]α-Bgt for binding to (a) muscle-type α1β1γδ nAChR from T. californica ray electric organ and (b) human neuronal α7 receptor expressed in GH4C1 cells. Each point presented on the inhibition curves was shown as mean ± SEM analyzed from triplicate. The calculated IC₅₀ values and Hill slopes (OriginPro 2015 program) are collected in Table 1.