| ATP | adenosine triphosphate |
| BOF | biomass objective function |
| CCLE | Cancer Cell Line Encyclopedia |
| COBRA | constraint-based reconstruction and analysis |
| CORDA | cost optimization reaction dependency assessment |
| COVID | coronavirus disease |
| EBI | European Bioinformatics Institute |
| EGA | European Genome-Phenome Archive |
| ENA | European Nucleotide Archive |
| FANTOM5 | Functional Annotation of the Mammalian Genome 5 |
| FASTCC | fast consistency checking |
| FBA | flux balance analysis |
| FVA | flux variability analysis |
| GEM | genome-scale metabolic model |
| GEO | Genome Expression Omnibus |
| GIM3E | gene inactivation moderated by metabolism, metabolomics and expression |
| GIMME | gene inactivity moderated by metabolism and expression |
| GIMMEp | gene inactivity moderated by metabolism and expression by proteome |
| GPR | gene-protein-reaction |
| GTEx | Genotype-Tissue Expression database |
| HPA | Human Protein Atlas |
| iMAT | integrative metabolic analysis tool |
| INIT | integrative network inference for tissues |
| LP | linear programming |
| MADE | metabolic adjustment by differential expression |
| MBA | model building algorithm |
| mCADRE | metabolic context-specificity assessed by deterministic reaction evaluation |
| METRADE | MEtabolic and TRanscriptomics ADaptation Estimator |
| MILP | mixed integer linear programming |
| MIQP | mixed integer quadratic programming |
| MTA | metabolic transformation algorithm |
| NCBI | National Center for Biotechnology Information |
| NGS | next-generation sequencing |
| NHBE | normal human bronchial epithelial |
| PCA | principal component analysis |
| PDC | Proteomic Data Commons |
| pFBA | parsimonious flux balance analysis |
| PRIME | personalized reconstructIon of metabolic models |
| QP | quadratic programming |
| RegrEx | regularized context-specific model extraction method |
| RIPTide | reaction inclusion by parsimony and transcript distribution |
| RMetD2 | relative metabolic differences version 2 |
| RMF | required metabolic function |
| RNA-seq | RNA sequencing |
| SARS-CoV-2 | Severe acute respiratory syndrome coronavirus 2 |
| scRNA-seq | single cell RNA sequencing |
| SRA | Sequence Read Archive |
| TCGA | The Cancer Genome Atlas |
| TIGER | toolbox for integrating genome-scale metabolism, expression, and regulation |
| tINIT | task-driven integrative network inference for tissues |
| TPM | transcripts per million |
| VBOF | viral biomass objective function |
| WBM | whole-body model |