Table 2.

Comparisons between HCs, AIHp and PBCp. For each pairwise comparison, two columns are reported: the first column shows the Mann—Whitney significant p-values, highlighted by color tones ranging from yellow to red; the second column shows the direction of the change. The last column on the right shows the results of the ANOVA-analogue nonparametric Kruskal—Wallis test.

Components		HCs vs. AIHp		HCs vs. PBCp		AIHp vs. PBCp		AIHp vs. PBCp vs. HCs
N	Description	Mann—Whitney		Mann—Whitney		Mann—Whitney		Kruskal—Wallis
		p-Value	Change	p-Value	Change	p-Value	Change	p-Value
1	S100A12					<0.05	PBC > AIH	<0.05
2	S100A8
3	S100A7D27					<0.05	PBC > AIH	<0.01
4	S100A9_short
5	S100A9_short_ox			<0.05	C > PBC			<0.05
6	S100A9_short_P							<0.05
7	S100A9_short_P_ox
8	Sum_S100A9_short_and_ox
9	Sum_S100A9_s_and_s_P
10	Sum_S100A9_s_P_and_P_ox
11	Sum_S100A9_s_ox_and_P_ox			<0.05	C > PBC			<0.05
12	Sum_S100A9_short			<0.05	C > PBC
13	S100A9_long_g
14	S100A9_long_g_p
15	S100A9_long_g_ox							<0.05
16	Sum_S100A9_long_g
17	Cystatin_A	<0.05	AIH > C			<0.05	AIH > PBC	<0.05
18	Cystatin_A_Acetyl
19	Cystatin_A_Acetyl_T96L
20	Sum_Cystatin_A	<0.05	AIH > C
21	Cystatin_B_S_glut
22	Cystatin_B_S_cyst
23	Cystatin_B_SSdimer
24	Cystatin_B_S_CMC
25	Sum_Cystatin_B
26	Cystatin_C			<0.05	PBC > C			<0.01
27	Cystatin_D_des_1_5
28	Cystatin_S
29	Cystatin_S1			<0.001	PBC > C	<0.01	PBC > AIH	<0.001
30	Cystatin_S2			<0.0001	PBC > C	<0.01	PBC > AIH	<0.0001
31	Cystatin_SN			<0.01	PBC > C	<0.05	PBC > AIH	<0.05
32	Cystatin_SN_des_1_4
33	Cystatin_SA
34	Cystatin_S1_ox	<0.001	AIH > C					<0.01
35	Cystatin_S2_ox
36	Cystatin_SN_ox
37	Sum_Cystatin_S1			<0.0001	PBC > C	<0.01	PBC > AIH	<0.0001
38	Sum_Cystatin_S2			<0.0001	PBC > C	<0.01	PBC > AIH	<0.0001
39	Sum_Cystatin_S_S1_S2			<0.0001	PBC > C	<0.001	PBC > AIH	<0.0001
40	Sum_Cystatin_SN			<0.01	PBC > C			<0.05
41	Sum_Cystatin_SA
42	Hst_1
43	Hst_1_0P
44	Sum_Hst_1
45	Hst_6	<0.01	AIH > C			<0.05	AIH > PBC
46	Hst_5	<0.05	AIH > C			<0.05	AIH > PBC	<0.05
47	Hst_3	<0.05	AIH > C			<0.01	AIH > PBC	<0.01
48	Sum_Hst_3	<0.01	AIH > C			<0.05	AIH > PBC	<0.05
49	Sum_Hst	<0.05	AIH > C					<0.05
50	α_defensin_1
51	α_defensin_2
52	α_defensin_3
53	α_defensin_4
54	Sum_α_defensins
55	PRP1_2P					<0.05	AIH > PBC
56	PRP1_1P
57	PRP1_0P
58	PRP1_3P			<0.01	PBC > C			<0.05
59	Sum_PRP1					<0.05	AIH > PBC
60	PRP3_2P
61	PRP3_1P			<0.05	C > PBC	<0.05	AIH > PBC	<0.05
62	PRP3_0P
63	PRP_3_diphos_Des_Arg106					<0.05	PBC > AIH	<0.05
64	Sum_PRP3
65	P_C_peptide
66	Statherin_2P	<0.05	AIH > C
67	Statherin_1P	<0.05	AIH > C			<0.05	AIH > PBC
68	Statherin_0P
69	Sum_Statherin	<0.05	AIH > C
70	PB_peptide					<0.01	AIH > PBC	<0.05
71	SLPI			<0.05	PBC > C			<0.05