Table 3.
Effects of GGOH and GTP supplementation on final body weights, white adipose tissue weights and adipokine concentrations.
| Parameters | -GGOH | +GGOH | Two-Way ANOVA p-Value | ||||
|---|---|---|---|---|---|---|---|
| -GTP (Control) |
+GTP (TP) |
-GTP (GG) |
+GTP (GGTP) |
GGOH | GTP | GGOH×GTP | |
| Final BW | 37.9 ax ± 1.30 | 34.3 ay ± 1.40 | 35.3 bx ± 1.40 | 31.5 by ± 1.40 | 0.049 | 0.009 | 0.960 |
| WAT weight (g) | 2.23 ax ± 0.16 | 1.75 ay ± 0.16 | 1.90 bx ± 0.16 | 1.36 by ± 0.16 | 0.031 | 0.003 | 0.870 |
| Resistin (pg/mg protein) | 253.4 x ± 43.2 | 63.5 y ± 4.4 | 238.4 x ± 26.5 | 149.0 y ± 17.8 | 0.202 | <0.001 | 0.073 |
| Leptin (pg/mg protein) | 37.8 x ± 8.1 | 5.7 y ± 1.4 | 29.8 x ± 3.4 | 10.4 y ± 1.8 | 0.712 | <0.001 | 0.176 |
| IL-6 (pg/mg protein) | 0.662 x ± 0.106 | 0.194 y ± 0.021 | 0.839 x ± 0.176 | 0.321 y ± 0.040 | 0.141 | <0.001 | 0.701 |
| MCP-1 (pg/mg protein) | 0.413 x ± 0.067 | 0.023 y ± 0.007 | 0.327 x ± 0.066 | 0.140 y ± 0.077 | 0.836 | <0.001 | 0.174 |
Different letters (a and b for GGOH effect; x and y for GTP effect) are significantly different by two-way ANOVA (p < 0.05). Values are mean (n = 12/group) with the standard error of mean (S.E.M.). Group assignment includes control group (high-fat diet group); TP group (high-fat diet and green tea polyphenols at 0.5% (v/w in drinking water)); GG group (high-fat diet and geranylgeraniol at 400 mg/kg diet); GGTP (high-fat diet, geranylgeraniol, and green tea polyphenols). Abbreviation: BW, body weight; GGOH, geranylgeraniol; GTP, green tea polyphenols; IL-6, ineterleukin-6; MCP-1, monocyte chemoattractant protein-1; WAT, white adipose tissue.