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. 2023 Jan 5;24(2):1028. doi: 10.3390/ijms24021028

Table 2.

Associations between the tag SNPs in and around the TRPC3 gene and chronic pain, comparing the genotype distributions between patients and control subjects.

# Corresponding to Figure 1 SNP Genotype Number of Participants χ 2
NPPG NOCG p
#2 rs1507994 GG 112 177 0.816
GA 73 97 0.665
AA 6 8
#3 rs13145213 GG 33 46 0.888
GA 99 135 0.642
AA 56 93
#7 rs11726196 TT 14 5 14.0559
TG 69 80 0.00089 *
GG 108 197
#8 rs2135976 GG 165 259 4.584
GA 25 23 0.101
AA 1 0
#9 rs11732666 AA 48 102 7.395
AG 109 129 0.025
GG 32 51
#10 rs17517624 AA 5 3 4.471
AG 49 55 0.107
GG 137 224
#11 rs3762839 TT 161 229 2.439
TG 30 50 0.295
GG 0 3
#12 rs884701 TT 52 102 5.324
TC 107 129 0.070
CC 32 51
#13 rs13127488 TT 32 50 5.098
TG 107 130 0.078
GG 52 102
#14 rs906496 AA 38 74 3.123
AG 103 132 0.210
GG 50 76
#22 rs1358229 AA 39 72 5.687
AG 106 125 0.058
GG 46 85
#23 rs6838639 TT 16 33 4.109
TC 100 122 0.128
CC 75 127
#26 rs6817255 AA 66 82 1.194
AC 87 136 0.551
CC 38 57
#27 rs11098653 AA 4 4 0.705
AG 49 80 0.703
GG 138 197
#28 rs13130390 CC 1 3 0.692
CT 33 54 0.708
TT 157 225

# Matches the number in Figure 1. NPPG and NOCG indicate the neuropathic pain patient group and the nociceptive control subject group, respectively. Three × 2 χ2 tests were conducted to compare the neuropathic pain patients and control subjects among the genotypes in each SNP. * Statistically significant differences between the neuropathic pain patients and control subjects. The p values in the table are the crude values without the Bonferroni correction.