Figure 6.

Mass spectrometric analysis of individual venoms. (A) Venom protein families and subfamilies identified in each venom by shotgun proteomic analysis. Bars represent total proteins identified, and colors indicate number of proteins in each protein family. (B) Summed intensities of peptides per protein family and subfamily for venom proteins. Intensities of each shared peptide in an identified protein were summed based on protein family and subfamily and used for relative quantitative comparison of protein abundances between the different venoms. Abbreviations: bradykinin-potentiating peptides (BPP); cysteine-rich secretory protein (CRISP); C-type lectin (CTL); glutaminyl-peptide cyclotransferase (GPC); hyaluronidase (Hyal); L-amino acid oxidase (LAAO); nerve growth factor (NGF); 5′ nucleotidase (NTD); phosphodiesterase (PDE); PI, PII, PIII snake venom metalloprotease (PI, PII, PIII SVMP); phospholipase A₂ (PLA₂); phospholipase B (PLB); (SVSP); thrombin-like serine proteinase (TLE); vascular endothelial growth factor (VEGF).