Figure 1.

The effect of rhPEPD on cell viability in experimental model of inflammation induced by IL-1β in fibroblasts. Cells were treated with various concentrations of rhPEPD in the absence or presence of IL-1β (10 ng/mL) for 24 h (A) and 48 h (B), followed by MTT assay. The mean values ± S.D. of three experiments carried out in duplicate are presented. The results are significant at p < 0.05, represented by ^, *, and #; ^ indicates significance vs. control (0 nM of PEPD without IL-1β), * indicates significance vs. control (0 nM of PEPD with IL-1β), and # indicates significance between groups treated with and without IL-1β.