Table 1.
In vitro model of antimicrobial efficacy of SynBalance® Femme vs. C. glabrata ATCC 15126, N. gonhorreae ATCC 43069 or T. vaginalis ATCC 30238 on HVE. The amount of SynBalance® Femme and each pathogen was expressed as log10 CFU/mL. The epithelium viability was expressed in percentage, while the TEER in Ohm × cm2. All the experiments were carried out in triplicate.
| Protocol A | SynBalance® Femme |
C. glabrata | SynBalance® Femme | N. gonhorreae | SynBalance® Femme | T. vaginalis |
|---|---|---|---|---|---|---|
| Initial count | 7.74 | 7.75 | 7.47 | 7.81 | 7.96 | 7.49 |
| Non-adhered microrganism (washing) | 6.68 | 7.75 | 0 | 0 | 4.60 | 0 |
| Adhered microrganism (homogenates) | 7.30 | 5.43 | 6.10 | 4.69 | 6.68 | 0 |
| Microrganism penetrated into the epithelium (medium) | 0 | 0 | 0 | 0 | 0 | 0 |
| Epithelium viability (%) | 99.0 | - | 98.7 | - | 98.7 | - |
| Epithelium integrity (TEER, Ω) | 173.3 | - | 175.4 | - | 173.8 | - |
- not performed.