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. 2022 Dec 22;15(1):36. doi: 10.3390/pharmaceutics15010036

Figure 4.

Figure 4

(d) Photostimulation of intranasal delivery of liposomes to GBM: (a,b) Representative images of the mouse brain with GBM (red, Ex 561/Em 570–620) 3 h after intranasal administration of liposomes (green, Ex 488/Em 500–550) in mice not treated (a) and treated by laser (b), the blood vessels were filled with the Evans Blue dye (blue, Ex 640/Em 663–738); (c) the quantitative analysis of fluorescent signal from liposomes (a.u.) in the GBM tissues in the GBM + laser and the GBM groups, n = 7 in each group, ** p < 0.01, the Mann–Whitney–Wilcoxon test, the outliers of experimental data are plotted using the ‘+’ symbol.