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. 2022 Dec 31;13(1):121. doi: 10.3390/life13010121

Figure 3.

Figure 3

A timeline of experimental evidence of how EVs are involved in the spread of misfolded proteins, and how miRNA alter cellular phenotypes, in ALS cell-based and animal models. Abbreviations: MN-motor neuron, DPR-dipeptide repeat proteins [82,83,84,85,86,87,88,89,90,91,92,93,94]. Figure created using Biorender.com.