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. 2023 Jan 12;28(2):757. doi: 10.3390/molecules28020757

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Toxicity assay after 24 h incubation of PBMCs with KB-151 and KB-208. MTT (right) and LDH (left) results for PBMC using high concentration (up to 250 µM) of KB-151 (black) and KB-208 (grey). Y-axis for MTT graph shows the percentage of metabolic activity which is related to the cell viability and for LDH graph, shows the percentage of relative specific death which related to the cell toxicity. X-axis of both MTT and LDH show different concentrations of KB-151 and KB-208, Thimerosal at 100 µM as control toxicity (* p < 0.05, ** p < 0.01, *** p < 0.001 and **** p < 0.0001), and untreated control. Bars represent mean ± SD, and N = 3.