Table 1.

Synthesis of several CCBs created by lipophilic alkyl and aryl substitutions.

Product	Substituents
	R = CH3, OCH3, OCH2CH3
	R1 = CH2CH2CH3, CH2CH2OCH3, CH3, H R2 = CH2CH2CH3, CH2CH2OCH3, CH2C6H5, CH2CH(C6H5)2
	R = C6H5, pCH3C6H4, pBrC6H4
	R1 = H, R2 =C6H5, pNO2C6H4 R1 = R2 = C6H5
	X = O, R = C6H5, pCH3C6H4 X = S, R = CH2CH=CH2, pNO2C6H4, CH(C6H5)2
	R = CH2C6H5, CH2COC6H5
	X = O, R = CH3, C2H5, C(CH3)3, CH2C≡CH X = S, R = C6H5