Schematic showing the domains of the Rv1818c gene from M. tuberculosis H37Rv used to clone the intact gene, 1818PE_PGRS, and its N-terminal PE region, 1818PE, in expression plasmids. In the sequence of Rv1818c, the amino acids found in the 1818PE construct are shown in italics, while the signature PE sequence and the 26 -GGAGG- repeats found in the PGRS domain are underlined.