Table 1.
Participant demographics and clinical data.
| Characteristics | Healthy Controls | bvFTD | svPPA | Test Statistic | p-value |
|---|---|---|---|---|---|
|
| |||||
| n | 21 | 24 | 16 | ||
| Age | 70.1 (6.3) | 65.2 (8.3) | 64.7 (6.2) | F(2,58)=3.57 | .03 |
| Sex (Male/Female) | 9/12 | 15/9 | 6/10 | χ2(2, N=61)=2.91 | .23 |
| Education | 16.3 (3.5) | 16.3 (3.5) | 17.9 (3.1) | F(2,56)=2.18 | .13 |
| CDR Total Score (0–3) | 0.0 (0.1) | 1.3 (0.6) | 0.8 (0.4) | F(1,38)=11.01 | <.01 |
| CDR-SOB (0–12) | 0.1 (0.3) | 7.2 (2.7) | 4.2 (2.2) | F(1,38)=13.89 | <.001 |
| MMSE (0–30) | 29.1 (1.2) | 25.3 (3.3) | 23.3 (4.7) | F(1,38)=2.49 | .12 |
| PPVT (0–16) | 16.0 (0) | 14.5 (1.7) | 10.6 (2.6) | F(1,33)=30.07 | <.001 |
| BNT (0–15) | 14.8 (0.5) | 12.8 (2.9) | 5.1 (3.2) | F(1,37)=64.45 | <.001 |
| Psychiatric medications (Y/N) | 2/19 | 18/6 | 11/5 | χ2(1, N=40)=.19 | .66 |
Statistical comparisons were limited to the bvFTD and svPPA groups for the clinical measures (i.e., CDR Total Score, CDR-SOB, MMSE, PPVT, BNT, and psychiatric medications) due to heterogeneity of variance in the healthy control group. bvFTD=behavioral variant frontotemporal dementia, svPPA=semantic variant primary progressive aphasia, MMSE=Mini-Mental State Examination, CDR=Clinical Dementia Rating scale; CDR-SOB=Clinical Dementia Rating – Sum of Boxes; PPVT=Peabody Picture Vocabulary Test; BNT=Boston Naming Test. Means (and standard deviations) included unless otherwise noted.