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. 2023 Jan 14;2023:9966355. doi: 10.1155/2023/9966355

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Copyright © 2023 Wei Zhang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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TBM protected against DOX-induced oxidative stress in mice. (a, b) DHE staining indicated the generation of ROS in mice hearts (n = 6). (c) The MDA levels in mouse hearts (n = 6). (d, e) The activity of SOD and GSH-PX in mouse hearts (n = 6). (f–h) The mRNA levels of Nrf2, Ho-1, and Nqo1 in mice determined by qPCR (n = 6). (i–m) Western blotting analysis of Nrf2, HO-1, and NQO1 at the protein level (n = 6). Values indicate the mean ± SD. ∗P < 0.05 versus the CON group and the TBM group; ^#P < 0.05 versus the DOX group; ns (not significant) versus the CON group.