Table 1.
logFC | AveExpr | t | P value | Adj. P.Val | B | Sig | Gene_name |
---|---|---|---|---|---|---|---|
2.766981 | 10.02813 | 24.83617 | 1.59E−71 | 2.41E−67 | 152.2407 | Up | CDH3 |
3.51672 | 8.149571 | 24.37658 | 5.15E−70 | 3.91E−66 | 148.795 | Up | IL13RA2 |
4.22487 | 4.938856 | 22.84845 | 6.52E−65 | 3.30E−61 | 137.1561 | Up | IGFL2 |
3.364436 | 10.60868 | 22.74715 | 1.43E−64 | 5.44E−61 | 136.375 | Up | COMP |
4.365315 | 7.774525 | 22.39132 | 2.30E−63 | 6.99E−60 | 133.6222 | Up | COL17A1 |
− 2.23625 | 7.195647 | − 21.9088 | 1.02E−61 | 2.58E−58 | 129.8669 | Down | CTNND2 |
2.991574 | 8.057767 | 21.5496 | 1.73E−60 | 3.76E−57 | 127.0559 | Up | HS6ST2 |
2.760018 | 8.75285 | 21.38315 | 6.48E−60 | 1.23E−56 | 125.7486 | Up | DIO2 |
2.487672 | 8.386943 | 20.96768 | 1.76E−58 | 2.97E−55 | 122.4737 | Up | ADAMTS14 |
2.657568 | 6.986265 | 20.47869 | 8.76E−57 | 1.33E−53 | 118.5982 | Up | SCG5 |
− 2.17148 | 6.87585 | − 20.4486 | 1.12E−56 | 1.54E−53 | 118.3591 | Down | FAM167A |
2.976165 | 6.119909 | 19.82738 | 1.65E−54 | 1.79E−51 | 113.4033 | Up | TMEM229A |
− 2.06299 | 9.50816 | − 19.8031 | 2.00E−54 | 2.03E−51 | 113.209 | Down | CRTAC1 |
− 2.12757 | 10.86437 | − 19.6535 | 6.71E−54 | 6.36E−51 | 112.0103 | Down | C11orf9 |
2.87141 | 8.609686 | 18.7457 | 1.06E−50 | 7.31E−48 | 104.7026 | Up | TUBB3 |
2.362009 | 4.947451 | 18.45088 | 1.17E−49 | 7.41E−47 | 102.3176 | Up | FRMD5 |
2.572854 | 7.592293 | 18.30919 | 3.72E−49 | 2.17E−46 | 101.1696 | Up | TDO2 |
2.127251 | 10.95033 | 17.93908 | 7.67E−48 | 3.33E−45 | 98.16623 | Up | COL3A1 |
2.157614 | 9.930151 | 17.88617 | 1.18E−47 | 4.86E−45 | 97.7363 | Up | CTHRC1 |
3.561535 | 5.093026 | 17.76968 | 3.07E−47 | 1.20E−44 | 96.78941 | Up | SPRR1A |
3.745945 | 5.457904 | 17.76204 | 3.27E−47 | 1.21E−44 | 96.72732 | Up | GPR87 |
− 3.12637 | 5.905882 | − 16.8918 | 4.13E−44 | 1.05E−41 | 89.63863 | Down | SERTM1 |
3.032648 | 6.806622 | 16.80599 | 8.37E−44 | 1.95E−41 | 88.93822 | Up | CHRDL2 |
− 2.07597 | 11.46303 | − 16.7484 | 1.34E−43 | 3.00E−41 | 88.46867 | Down | FIGF |
3.160266 | 12.05447 | 16.70106 | 1.98E−43 | 4.24E−41 | 88.08196 | Up | MMP7 |
4.805732 | 9.414086 | 16.56306 | 6.16E−43 | 1.26E−40 | 86.95575 | Up | MMP1 |
2.037572 | 6.383056 | 16.42577 | 1.91E−42 | 3.49E−40 | 85.83511 | Up | P4HA3 |
− 2.19976 | 3.898955 | − 16.41 | 2.17E−42 | 3.92E−40 | 85.70644 | Down | DAO |
2.226205 | 4.358469 | 16.16479 | 1.63E−41 | 2.58E−39 | 83.70469 | Up | CPNE4 |
− 3.76646 | 10.06016 | − 16.1418 | 1.97E−41 | 3.08E−39 | 83.51712 | Down | ITLN2 |
− 2.90756 | 5.198867 | − 16.0732 | 3.46E−41 | 5.20E−39 | 82.95688 | Down | SLC5A9 |
− 2.2071 | 6.223977 | − 16.0238 | 5.20E−41 | 7.51E−39 | 82.55381 | Down | MATN3 |
2.47714 | 7.467569 | 15.99126 | 6.79E−41 | 9.63E−39 | 82.28814 | Up | MMP11 |
− 2.47715 | 14.60113 | − 15.9736 | 7.85E−41 | 1.10E−38 | 82.1439 | Down | AGER |
2.564527 | 6.131047 | 15.88976 | 1.56E−40 | 2.12E−38 | 81.45978 | Up | GJB2 |
− 2.24312 | 6.256766 | − 15.7125 | 6.72E−40 | 8.43E−38 | 80.01307 | Down | DPP6 |
2.684995 | 7.423303 | 15.60143 | 1.67E−39 | 1.97E−37 | 79.10736 | Up | SCRG1 |
− 2.3598 | 6.071668 | − 15.547 | 2.62E−39 | 2.96E−37 | 78.66324 | Down | CCK |
− 2.01366 | 5.110895 | − 15.4987 | 3.89E−39 | 4.25E−37 | 78.26978 | Down | RGS9BP |
− 2.53328 | 7.572299 | − 15.3963 | 9.02E−39 | 9.31E−37 | 77.43515 | Down | BTNL9 |
− 3.14081 | 9.246772 | − 15.3426 | 1.40E−38 | 1.37E−36 | 76.99693 | Down | CA4 |
− 2.01677 | 5.500521 | − 15.1519 | 6.70E−38 | 6.28E−36 | 75.44365 | Down | GRIA1 |
2.63809 | 9.547163 | 14.99355 | 2.46E−37 | 2.17E−35 | 74.15484 | Up | SFRP2 |
2.177063 | 9.87252 | 14.99053 | 2.52E−37 | 2.21E−35 | 74.13025 | Up | CILP |
− 2.51131 | 6.897446 | − 14.8662 | 6.97E−37 | 5.82E−35 | 73.11921 | Down | ARC |
2.977688 | 4.686335 | 14.70242 | 2.67E−36 | 2.05E−34 | 71.78832 | Up | GREM1 |
− 2.22583 | 10.08823 | − 14.5432 | 9.80E−36 | 6.79E−34 | 70.49599 | Down | CSRNP1 |
3.273104 | 5.371113 | 14.53062 | 1.09E−35 | 7.43E−34 | 70.39393 | Up | UGT1A6 |
2.048878 | 8.000404 | 14.40344 | 3.07E−35 | 1.99E−33 | 69.36293 | Up | PNOC |
2.458664 | 6.380619 | 14.35154 | 4.69E−35 | 2.93E−33 | 68.94254 | Up | KIAA0125 |
2.314409 | 11.53685 | 14.24544 | 1.11E−34 | 6.58E−33 | 68.08363 | Up | POU2AF1 |
2.810528 | 11.71609 | 14.16438 | 2.16E−34 | 1.23E−32 | 67.42805 | Up | KRT15 |
2.473771 | 8.42905 | 14.02724 | 6.59E−34 | 3.53E−32 | 66.32004 | Up | FCRL5 |
2.27024 | 11.15122 | 13.96948 | 1.05E−33 | 5.57E−32 | 65.85389 | Up | MZB1 |
− 2.57245 | 5.211454 | − 13.8693 | 2.38E−33 | 1.22E−31 | 65.04635 | Down | GRM8 |
2.231172 | 9.119239 | 13.8484 | 2.82E−33 | 1.41E−31 | 64.8776 | Up | TNFRSF17 |
2.756707 | 4.877502 | 13.78906 | 4.56E−33 | 2.23E−31 | 64.39965 | Up | PCSK1 |
− 2.62411 | 9.695784 | − 13.7279 | 7.49E−33 | 3.54E−31 | 63.90757 | Down | RTKN2 |
2.120844 | 5.910121 | 13.62829 | 1.68E−32 | 7.30E−31 | 63.10645 | Up | MEOX1 |
− 2.4414 | 9.822001 | − 13.5846 | 2.39E−32 | 1.02E−30 | 62.75567 | Down | VIPR1 |
2.240894 | 4.784055 | 13.50426 | 4.58E−32 | 1.90E−30 | 62.11065 | Up | OGDHL |
3.053751 | 8.157115 | 13.50421 | 4.58E−32 | 1.90E−30 | 62.11025 | Up | PLA2G2A |
2.129504 | 4.529648 | 13.49352 | 5.00E−32 | 2.04E−30 | 62.02447 | Up | HS6ST3 |
4.099913 | 8.125221 | 13.44575 | 7.35E−32 | 2.92E−30 | 61.6414 | Up | KRT5 |
2.02468 | 15.36297 | 13.43145 | 8.25E−32 | 3.26E−30 | 61.52684 | Up | IGLL1 |
2.957404 | 8.32699 | 13.37414 | 1.31E−31 | 5.08E−30 | 61.06769 | Up | SLN |
2.025418 | 6.606265 | 13.32849 | 1.89E−31 | 7.24E−30 | 60.7023 | Up | JSRP1 |
2.955387 | 8.370847 | 13.14 | 8.65E−31 | 3.07E−29 | 59.19618 | Up | KRT17 |
2.469841 | 4.782865 | 13.13835 | 8.76E−31 | 3.11E−29 | 59.183 | Up | ADAMTS16 |
2.665355 | 4.140607 | 13.11133 | 1.09E−30 | 3.82E−29 | 58.96753 | Up | DSC3 |
2.047263 | 6.544204 | 12.95095 | 3.95E−30 | 1.29E−28 | 57.69017 | Up | SIX4 |
2.162986 | 7.005848 | 12.79213 | 1.41E−29 | 4.33E−28 | 56.42886 | Up | KRT13 |
− 3.82993 | 6.855422 | − 12.7626 | 1.78E−29 | 5.42E−28 | 56.19501 | Down | SLC6A4 |
2.050099 | 3.420621 | 12.71757 | 2.55E−29 | 7.62E−28 | 55.83794 | Up | GLB1L3 |
3.327225 | 10.25723 | 12.398 | 3.25E−28 | 8.42E−27 | 53.31524 | Up | SPP1 |
2.365788 | 5.364215 | 12.3891 | 3.49E−28 | 9.01E−27 | 53.24522 | Up | NELL1 |
2.233526 | 8.432288 | 12.25826 | 9.84E−28 | 2.44E−26 | 52.21743 | Up | B3GNT3 |
3.18778 | 4.471553 | 11.73307 | 6.11E−26 | 1.23E−24 | 48.12406 | Up | KRT6C |
3.074268 | 6.14006 | 11.57827 | 2.04E−25 | 3.88E−24 | 46.92814 | Up | CXCL13 |
2.28213 | 8.169303 | 11.5444 | 2.66E−25 | 5.00E−24 | 46.6672 | Up | TNS4 |
2.552859 | 4.618913 | 11.52658 | 3.05E−25 | 5.69E−24 | 46.52998 | Up | CYP24A1 |
2.211397 | 9.229355 | 11.52258 | 3.15E−25 | 5.83E−24 | 46.49923 | Up | LGALS7 |
− 2.62597 | 6.240672 | − 11.4101 | 7.54E−25 | 1.34E−23 | 45.63487 | Down | HTR3C |
− 2.51063 | 7.189042 | − 11.27 | 2.22E−24 | 3.74E−23 | 44.56281 | Down | IL1RL1 |
− 2.18817 | 3.733392 | − 11.1975 | 3.89E−24 | 6.42E−23 | 44.00948 | Down | HMGCS2 |
2.191917 | 9.204335 | 11.16278 | 5.08E−24 | 8.26E−23 | 43.74504 | Up | SIX1 |
− 3.09117 | 10.64484 | − 11.15 | 5.60E−24 | 9.07E−23 | 43.64818 | Down | FOSB |
2.105424 | 5.55814 | 10.97058 | 2.21E−23 | 3.35E−22 | 42.2868 | Up | FCRLA |
3.006776 | 5.260356 | 10.94717 | 2.65E−23 | 3.95E−22 | 42.1098 | Up | MMP10 |
2.358111 | 5.915948 | 10.92789 | 3.07E−23 | 4.56E−22 | 41.96412 | Up | VSIG1 |
− 2.33134 | 4.765235 | − 10.7303 | 1.38E−22 | 1.94E−21 | 40.47703 | Down | ANKRD1 |
2.142038 | 8.747571 | 10.61317 | 3.34E−22 | 4.54E−21 | 39.60094 | Up | LCN2 |
− 3.46187 | 6.368909 | − 10.5444 | 5.60E−22 | 7.46E−21 | 39.08815 | Down | CSF3 |
− 2.07382 | 12.65793 | − 10.5361 | 5.96E−22 | 7.93E−21 | 39.02614 | Down | FCN3 |
2.170145 | 4.032137 | 10.39294 | 1.74E−21 | 2.20E−20 | 37.96391 | Up | GJB5 |
2.367125 | 5.052865 | 10.32556 | 2.88E−21 | 3.58E−20 | 37.4659 | Up | CCL7 |
2.482971 | 5.13548 | 10.24086 | 5.42E−21 | 6.52E−20 | 36.84194 | Up | TTR |
2.042244 | 6.607493 | 10.10804 | 1.45E−20 | 1.67E−19 | 35.86794 | Up | LGSN |
− 2.00184 | 5.891826 | − 10.0318 | 2.55E−20 | 2.86E−19 | 35.31159 | Down | ESM1 |
− 2.45081 | 3.630636 | − 9.81136 | 1.28E−19 | 1.35E−18 | 33.71326 | Down | CT45A1 |
2.731854 | 6.087442 | 9.800989 | 1.38E−19 | 1.45E−18 | 33.63845 | Up | C4orf7 |
2.314047 | 8.881864 | 9.489329 | 1.32E−18 | 1.24E−17 | 31.40884 | Up | SOX2 |
− 2.14701 | 4.465319 | − 9.47809 | 1.43E−18 | 1.34E−17 | 31.3291 | Down | FAM71A |
2.393 | 6.242972 | 9.406946 | 2.38E−18 | 2.19E−17 | 30.82539 | Up | VTCN1 |
2.153101 | 7.83975 | 9.367191 | 3.16E−18 | 2.87E−17 | 30.54476 | Up | RHOV |
2.167415 | 4.486344 | 9.272752 | 6.20E−18 | 5.49E−17 | 29.88051 | Up | CLCA2 |
2.043337 | 9.418979 | 9.156337 | 1.41E−17 | 1.21E−16 | 29.06646 | Up | MUC4 |
2.375417 | 5.44786 | 9.103523 | 2.05E−17 | 1.74E−16 | 28.69891 | Up | KLK12 |
3.702802 | 10.68933 | 9.001632 | 4.19E−17 | 3.42E−16 | 27.993 | Up | BPIFB1 |
2.28831 | 5.361617 | 8.85303 | 1.18E−16 | 9.28E−16 | 26.97114 | Up | CXCL6 |
2.101133 | 5.911965 | 8.786643 | 1.87E−16 | 1.44E−15 | 26.51762 | Up | ATP12A |
2.155802 | 8.151967 | 8.776072 | 2.01E−16 | 1.55E−15 | 26.44557 | Up | CCNO |
2.039754 | 9.860517 | 8.654708 | 4.63E−16 | 3.42E−15 | 25.62194 | Up | GSTA5 |
2.296708 | 7.418001 | 8.454847 | 1.81E−15 | 1.25E−14 | 24.27972 | Up | MUC5B |
2.387684 | 7.938451 | 8.354771 | 3.55E−15 | 2.39E−14 | 23.61443 | Up | C10orf81 |
2.152617 | 6.603537 | 8.293087 | 5.37E−15 | 3.56E−14 | 23.20668 | Up | SRD5A2 |
2.254316 | 5.652982 | 8.087896 | 2.10E−14 | 1.31E−13 | 21.86327 | Up | MUC16 |
3.0035 | 6.116775 | 7.994348 | 3.89E−14 | 2.36E−13 | 21.25755 | Up | SERPINB3 |
2.920143 | 5.986109 | 7.948002 | 5.26E−14 | 3.14E−13 | 20.95907 | Up | SERPINB4 |
2.467293 | 8.119221 | 7.861204 | 9.26E−14 | 5.38E−13 | 20.40295 | Up | PIP |
2.301349 | 7.277284 | 7.813318 | 1.26E−13 | 7.25E−13 | 20.09778 | Up | TSPAN19 |
2.126246 | 10.9766 | 7.618692 | 4.41E−13 | 2.38E−12 | 18.86961 | Up | TMEM190 |
2.063954 | 7.274754 | 7.426121 | 1.49E−12 | 7.59E−12 | 17.67409 | Up | ZBBX |
3.187369 | 7.263725 | 7.35898 | 2.26E−12 | 1.14E−11 | 17.26199 | Up | MSMB |
2.878548 | 9.958996 | 4.790707 | 2.75E−06 | 7.11E−06 | 3.614207 | Up | RPS4Y1 |
2.805762 | 9.788328 | 4.671305 | 4.74E−06 | 1.19E−05 | 3.092936 | Up | RPS4Y2 |