Table 2.
Association of patient characteristics with outcome of IVT ischemic stroke.
| Mortality (n = 278) | Excellent functional (n = 636) | Functional outcome (n = 552) | Local hemorrhage (n = 67) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Yes (%) | No (%) | p | Yes | No | p | Yes | No | p | Yes | No | p | |
| Age-year. no (%) | ||||||||||||
| < 70 | 737 (57.22) | 80 (28.78) | < 0.001 | 586 (63.01) | 231 (36.32) | < 0.001 | 633 (62.43) | 184 (33.33) | < 0.001 | 28 (41.79) | 745 (53.06) | 0.071 |
| ≥ 70 | 551 (73.56) | 198 (71.22) | 344 (36.99) | 405 (63.68) | 381 (37.57) | 368 (66.67) | 39 (58.21) | 659 (46.94) | ||||
| Gender.no (%) | ||||||||||||
| Male | 144 (51.80) | 696 (54.04) | 0.497 | 554 (54.64) | 286 (51.81) | 0.284 | 508 (54.62) | 332 (52.20) | 0.345 | 40 (59.70) | 750 (53.42) | 0.314 |
| Female | 134 (48.20) | 592 (55.96) | 460 (45.36) | 266 (48.19) | 422 (45.38) | 304 (47.80) | 27 (40.30) | 654 (46.58) | ||||
| Vascular territory.no (%) | ||||||||||||
| ACS | 268 (96.40) | 1226 (95.19) | 0.380 | 882 (94.84) | 612 (96.23) | 0.198 | 965 (95.17) | 529 (95.83) | 0.548 | 64 (95.52) | 1340 (95.44)) | 0.975 |
| PCS | 10 (3.60) | 62 (4.81) | 48 (5.16) | 24 (3.77) | 49 (4.83) | 23 (4.17) | 3 (4.48) | 64 (4.56) | ||||
| Hypertension.no (%) | ||||||||||||
| Yes | 254 (92.36) | 1107 (86.08) | 0.005 | 794 (85.47) | 567 (89.72) | 0.014 | 863 (85.19) | 498 (90.88) | 0.001 | 55 (83.33) | 1230 (87.79) | 0.283 |
| No | 21 (7.64) | 179 (13.92) | 135 (14.53) | 65 (10.28) | 150 (14.81) | 50 (9.12) | 11 (16.67) | 171 (12.21) | ||||
| Diabetes mellitus.no (%) | ||||||||||||
| Yes | 160 (63.75) | 601 (49.30) | < 0.001 | 408 (46.15) | 353 (60.24) | < 0.001 | 452 (47.08) | 309 (60.59) | < 0.001 | 35 (56.45) | 680 (51.44) | 0.440 |
| No | 91 (36.25) | 618 (50.70) | 476 (53.85) | 233 (39.76) | 508 (52.92) | 201 (39.41) | 27 (43.55) | 642 (48.56) | ||||
| Atrial fibrillation | ||||||||||||
| Yes | 56 (20.51) | 162 (12.58) | 0.001 | 106 (11.40) | 112 (17.75) | < 0.001 | 118 (11.64) | 100 (18.28) | < 0.001 | 21 (32.81) | 182 (12.98) | < 0.001 |
| No | 217 (79.49) | 1126 (87.42) | 824 (88.60) | 519 (82.25) | 896 (88.36) | 447 (81.72) | 43 (67.19) | 1220 (87.02) | ||||
| Cigarette smoking | ||||||||||||
| Yes | 21 (7.66) | 137 (10.68) | 0.134 | 99 (10.68) | 59 (9.37) | 0.399 | 109 (10.79) | 49 (8.96) | 0.253 | 6 (9.38) | 138 (9.87) | 0.896 |
| No | 253 (92.34) | 1146 (89.32) | 828 (89.32) | 571 (90.63) | 901 (89.21) | 498 (91.04) | 58 (90.63) | 1260 (90.13) | ||||
| NIHSS baseline score | ||||||||||||
| Low (< 6) | 10 (4.10) | 309 (28.85) | < 0.001 | 269 (35.30) | 50 (6.09) | < 0.001 | 283 (33.57) | 36 (7.63) | < 0.001 | 3 (6.38) | 302 (25.21) | < 0.001 |
| Low-middle (6–14) | 68 (27.87) | 501 (46.78) | 369 (48.43) | 200 (36.17) | 414 (49.11) | 155 (32.84) | 10 (21.28) | 534 (44.57) | ||||
| Middle-high (15–24) | 145 (59.43) | 233 (21.76) | 113 (14.83) | 265 (47.92) | 133 (15.78) | 245 (51.91) | 29 (61.70) | 322 (26.88) | ||||
| High (≥ 25) | 21 (8.61) | 28 (2.61) | 11 (1.44) | 38 (6.87) | 13 (1.54) | 36 (7.63) | 5 (10.64) | 40 (3.34) | ||||
| Duration of admission, (Mean ± SD) | 13.55 ± 15.30 | 7.57 ± 9.50 | < 0.001 | 6.20 ± 6.82 | 12.16 ± 14.43 | < 0.001 | 6.18 ± 6.63 | 13.11 ± 15.19 | < 0.001 | 17. 08 ± 16.57 | 8. 27 ± 10.57 | < 0.001 |
| Type of Ischemic stroke | ||||||||||||
| Large vessel | 60 (21.98) | 160 (12.44) | < 0.001 | 116 (12.50) | 104 (16.48) | < 0.001 | 129 (12.75) | 91 (16.64) | < 0.001 | 4 (6.15) | 193 (13.80) | < 0.001 |
| Other large | 125 (45.79) | 665 (51.71) | 480 (51.72) | 310 (49.13) | 521 (51.48) | 269 (49.18) | 19 (29.23) | 737 (52.68) | ||||
| Embolic | 18 (6.59) | 89 (6.92) | 53 (5.71) | 54 (8.56) | 61 (6.03) | 46 (8.41) | 10 (15.38) | 88 (6.29) | ||||
| Small | 13 (4.76) | 181 (14.07) | 151 (16.27) | 43 (6.81) | 160 (15.81) | 34 (6.22) | 2 (0.08) | 187 (13.37) | ||||
| Other | 57 (20.88) | 191 (14.85) | 128 (13.790 | 120 (19.02) | 141 (13.93) | 107 (19.56) | 30 (46.15) | 194 (13.87) | ||||