Table 2.
The proportions of platelets present with the indicated triple marker phenotypes, based on annexin-V (AnnV), CD42b and CD62P.
| Fluorescent marker combination (%) | ||||||||
|---|---|---|---|---|---|---|---|---|
| AnnV− | AnnV+ | |||||||
| Treatment group | CD42b+ CD62P− | CD42b+ CD62P+ | CD42b− CD62P− | CD42b− CD62P+ | CD42b+ CD62P− | CD42b+ CD62P+ | CD42b− CD62P− | CD42b− CD62P+ |
| Unstimulated | 73 ± 9 | 20 ± 6 | 1 ± 0 | 0 ± 0 | 0 ± 0 | 2 ± 1 | 0 ± 0 | 0 ± 0 |
| C&T | 2 ± 0 | 62 ± 10 | 2 ± 1 | 1 ± 1 | 3 ± 1 | 29 ± 8 | 1 ± 0 | 0 ± 0 |
| A23187 | 2 ± 1 | 6 ± 6 | 1 ± 1 | 0 ± 0 | 17 ± 11 | 72 ± 9 | 1 ± 1 | 1 ± 1 |
| ABT-737 | 0 ± 0 | 0 ± 0 | 1 ± 0 | 1 ± 0 | 0 ± 0 | 0 ± 0 | 90 ± 3 | 7 ± 3 |
| Cryopreserved | 6 ± 4 | 11 ± 5 | 2 ± 1 | 0 ± 0 | 56 ± 8 | 23 ± 7 | 2 ± 2 | 0 ± 0 |
| Subpopulation | Resting | Aggregatory | N/A | N/A | Novel | Procoagulant | Apoptotic | N/A |
Data shown as mean ± SD; n = 6 in each group.
Bolded cells indicate the dominant phenotype(s) within the treatment group.
N/A indicates a minority phenotype not associated with a subpopulation.
Novel indicates a phenotype not aligned with the known subpopulations.