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. Author manuscript; available in PMC: 2023 Feb 4.
Published in final edited form as: J Nephrol. 2022 Jul 22;36(1):83–91. doi: 10.1007/s40620-022-01361-6

Fig. 1.

Fig. 1

Changes in plasma concentrations of kynurenine pathway intermediates (A–D) across the investigated study groups: healthy children, children with ADPKD (normal eGFR), healthy adults and adults with ADPKD (eGFR above or below 60 mL/min/1.73m2, respectively). All concentrations are presented as ng/mL, except for tryptophan (calculated in μg/mL) and MCP-1 (calculated in pg/mL). Significance levels (after Bonferroni adjustment): healthy subjects versus ADPKD patients (children and adults, respectively): *p < 0.0056, ***p < 0.0001 and children versus adults with ADPKD: #p < 0.0056, ###p < 0.0001