Table 2.
Comparison of CEUS characteristics in nodules with different tumor size
| Indicator | ≤ 10 mm | p | > 10 mm | p | ||
|---|---|---|---|---|---|---|
| Benign | Malignant | Benign | Malignant | |||
| Wash-in | 0.736* | 0.161* | ||||
| Earlier | 0 (0.0%) | 0 (0.0%) | 7 (31.8%) | 1 (11.1%) | ||
| Meantime | 15 (71.4%) | 17 (77.3%) | 15 (68.2%) | 7 (77.8%) | ||
| Later | 6 (28.6%) | 5 (22.7%) | 0 (0.0%) | 1 (11.1%) | ||
| Intensity | 0.124* | 0.365* | ||||
| Hypo-enhancement | 2 (9.5%) | 8 (36.4%) | 0 (0.0%) | 1 (11.1%) | ||
| Iso-enhancement | 14 (66.7%) | 10 (45.5%) | 13 (59.1%) | 4 (44.4%) | ||
| Hyper-enhancement | 5 (23.8%) | 4 (18.2%) | 9 (40.9%) | 4 (44.4%) | ||
| Homogeneity | 1.000* | 0.063* | ||||
| Homogeneity | 19 (90.5%) | 19 (86.4%) | 21 (95.5%) | 6 (66.7%) | ||
| Heterogeneity | 2 (9.5%) | 3 (13.6%) | 1 (4.5%) | 3 (33.3%) | ||
| Enhanced defect | 0.185* | 0.826* | ||||
| Without | 17 (81.0%) | 21 (95.5%) | 12 (54.5%) | 6 (66.7%) | ||
| With | 4 (19.0%) | 1 (4.5%) | 10 (45.5%) | 3 (33.3%) | ||
| Enhanced pattern | 1.000* | 0.290* | ||||
| Entire | 18 (85.7%) | 19 (86.4%) | 22 (100.0%) | 8 (88.9%) | ||
| Centripetal | 1 (4.8%) | 2 (9.1%) | 0 (0.0%) | 0 (0.0%) | ||
| Eccentrical | 2 (9.5%) | 1 (4.5%) | 0 (0.0%) | 1 (11.1%) | ||
| Enhancing ring | 0.763* | 0.004* | ||||
| Without | 9 (42.9%) | 11 (50.0%) | 9 (40.9%) | 3 (33.3%) | 0.221# | |
| High | 1 (4.8%) | 0 (0.0%) | 10 (15.5%) | 0 (0.0%) | 0.003# | |
| Low | 11 (52.4%) | 11 (50.0%) | 3 (13.6%) | 6 (66.7%) | 0.087# | |
| Wash out | 0.656* | 0.287* | ||||
| Earlier | 6 (28.6%) | 4 (18.2%) | 4 (18.2%) | 4 (44.4%) | ||
| Later | 15 (71.4%) | 18 (81.8%) | 18 (81.8%) | 5 (55.6%) | ||
*Determined with the χ2 test
#Bonferroni correction was used for comparisons of the three categories, and values of p < 0.017 (0.05/3) were considered statistically significant for the pairwise comparisons