Table 2.
Relative abundance of PrPC proteoforms in the brain of the rodent models analyzed
| Line | Percent of PrPC proteoforms on total PrPC (mean ± SD) |
|||||
|---|---|---|---|---|---|---|
| FL-PrP | sFL | C2 | C1 | N1 | N2 | |
| Bank vole | 25.05 ± 1.35 | 6.65 ± 0.69 | 16.88 ± 1.08 | 49.94 ± 0.39 | 1.08 ± 0.37 | 0.39 ± 0.12 |
| C57Black | 22.81 ± 1.54 | 10.74 ± 2.95 | 11.74 ± 3.06 | 50.22 ± 3.60 | 3.53 ± 1.54 | 0.96 ± 0.45 |
| Tg338 | 23.31 ± 2.42 | 7.19 ± 0.41 | 14.71 ± 1.68 | 50.65 ± 1.54 | 2.99 ± 0.79 | 1.15 ±0.20 |
| Tg501 | 23.45 ± 0.99 | 8.08 ± 1.26 | 18.81 ± 2.31 | 44.78 ± 2.42 | 3.64 ± 1.16 | 1.23 ± 0.29 |
| Tg110 | 23.38 ± 0.17 | 7.14 ± 0.64 | 13.57 ± 1.67 | 52.29 ± 3.63 | 2.42 ± 0.89 | 1.20 ± 0.58 |
| Tg340 | 21.65 ± 0.21 | 9.01 ± 0.98 | 11.76 ± 2.35 | 52.36 ± 3.99 | 3.72 ± 1.53 | 1.50 ± 0.43 |
| Tg361 | 29.05 ± 1.87 | 7.70 ± 0.07 | 15.97 ± 2.43 | 43.39 ± 3.23 | 2.59 ± 0.68 | 1.30 ± 0.33 |