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. Author manuscript; available in PMC: 2023 Jan 23.
Published in final edited form as: Clin Cancer Res. 2019 Oct 3;26(3):598–607. doi: 10.1158/1078-0432.CCR-19-0972

Figure 1.

Figure 1.

Increased IL12 gene and protein expression posttherapy in electroporated lesions. A, IL12 gene expression (IL12A subunit) was elevated in several tumors posttreatment compared with pretreatment. Changes in gene expression were analyzed using NanoString nCounter platform. B, Paired pre- and post-biopsy samples from 10 patients were evaluable for IL12 p70 protein levels by MAGPIX. Data are presented as fold change (post-/pretreatment). The majority (6 of 10; 60%) had greater than 2-fold increase in IL12 protein levels suggesting sustained expression (at day 22) after treatment on days 1, 5, and 8. no., number.