Table 1.
Clinico-hematological parameters of patients with chronic lymphocyticleukaemia
| Parameter | No. of patients (%) or median (range) |
|---|---|
| Age (years) | 57 (30–75) |
| Sex | |
| Male | 84 (70%) |
| Female | 36 (30%) |
| Absolute lymphocyte count (× 109/L) | 55.9 (23–410) |
| Haemoglobin (g/dL) | 11.1 (4–14) |
| Platelet count (× 10 9/L) | 110 (10–390) |
| Rai Stage | |
| Stage II | 30 (25%) |
| Stage III | 42 (35%) |
| Stage IV | 48 (40%) |
| Flow cytometry markers | |
| ZAP70positive (n = 102) | 51 (50%) |
| CD38 positive* (n = 99) | 33 (33%) |
| CD49d positive^ (n = 96) | 47 (49%) |
| Beta-2 microglobulin (≥ 3.5 mg/L)(n = 90) | 72 (80%) |
| Mutated IGHV status (n = 110) | 55 (50%) |
| Comorbidities | 22 (18.3%) |
ZAP70 Zeta-chain associated protein kinase-70 (positivity cut-off 20%), CD Cluster of differentiation, IGHV Immunoglobulin heavy chain variable region
*CD38 positivity cut-off > 20%, ^CD49d positivity cut-off > 30%,