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. Author manuscript; available in PMC: 2024 Feb 1.
Published in final edited form as: Biomaterials. 2022 Dec 24;293:121960. doi: 10.1016/j.biomaterials.2022.121960

Figure 1. Schematic of decellularized lung processing for mass spectrometry.

Figure 1.

(A) H&E staining of native (non-decellularized) human patient lungs showing lung morphology, including emphysematous regions in COPD patient lung and fibrotic regions in IPF patient lungs. Representative image of decellularized normal lung on ventral (B) and dorsal (C) side. Representative image of isolated airway (D) and vascular (E) trees. (F) Liquid nitrogen milled ECM powders of whole decellularized lung ECM (wECM), as well as ECM from alveolar-enriched (aECM), airway-enriched (airECM), and vasculature-enriched (vECM) regions.