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. 2023 Jan 9;9:1096203. doi: 10.3389/fmed.2022.1096203

TABLE 4.

Most common treatment regimens per myositis antibody.

Auto-antibodies Pulses CS RTX MMF Azathioprine Cyclophosphamide IVIG MTX
Anti-Jo-1 6 (30.0%) 12 (60.0%) 5 (25.0%) 4 (20.0%) 2 (10.0%) 3 (15.0%) 4 (20.0%)
Anti-MDA5 7 (50.0%) 4 (28.6%) 5 (35.7%) 2 (14.3%) 6 (42.9%) 5 (35.7%) 1 (7.1%)
Anti-PL-7 4 (36.4%) 4 (36.4%) 4 (36.4%) 1 (9.1%) 1 (9.1%) 2 (18.2%) 0 (0%)
Anti-PL-12 4 (36.4%) 8 (72.3%) 4 (36.4%) 3 (27.3%) 3 (27.3%) 0 (0%) 0 (0%)
Anti-OJ 2 (22.2%) 6 (54.5%) 2 (22.2%) 2 (22.2%) 1 (11.1%) 0 (0%) 0 (0%)

CS, corticosteroids; Jo-1, Histidyl-tRNA synthetase; IVIG, intravenous immune globulin; MDA5, melanoma differentiation-associated gene 5; MMF, mycophenolate mofetil; MTX, methotrexate; OJ, Isoleucyl-tRNA synthetase; PL-7, Threonyl-tRNA synthetase antibodies; PL-12, Alanyl-tRNA synthetase; RTX, rituximab.