Skip to main content
. 2022 Oct 11;12:245–262. doi: 10.1016/j.aninu.2022.09.010

Table 7.

Effects of dietary coated essential oil and organic mixture supplementation on gene expressions of TLR signaling pathway-related genes in the jejunum of broiler chickens challenged with E. coli O78.

Item E. coli1 TLR-4 MyD88 NF-κB IFN-γ TNF-α IL-1β IL-8 IL-10
EOA, mg/kg
 0 - 1.07 1.02 1.06 1.01 1.00 1.05 1.04 1.07b
 0 + 1.92 1.18 1.04 2.74 1.04 1.12 1.38 0.72b
 500 - 1.18 1.11 1.16 1.13 1.32 1.02 0.75 0.81b
 500 + 1.31 1.22 1.03 1.06 1.13 1.09 1.96 1.84a
 SEM2 0.10 0.08 0.09 0.09 0.06 0.14 0.32 0.11
Main effect
 0 1.50 1.10 1.05 1.87 1.02 1.09 1.21 0.90
 500 1.20 1.17 1.10 1.09 1.23 1.05 1.36 1.33
 Non-challenged 1.13 1.07 1.11 1.07 1.16 1.04 0.90 0.94
 Challenged 1.66 1.20 1.03 1.90 1.09 1.10 1.67 1.28
P-value2
 EOA 0.377 0.663 0.805 0.408 0.095 0.905 0.821 0.055
 Challenged 0.032 0.407 0.676 0.016 0.524 0.803 0.013 0.126
 Challenged × EOA 0.567 0.877 0.747 <0.01 0.353 0.998 0.237 <0.01

TLR = toll-like receptor; MyD88 = myeloid differential protein-88; NF-κB = nuclear factor kappa-light-chain-enhancer of activated B cells; TNF-α = tumor necrosis factor α; IL = interleukin; IFN-γ = interferon γ; SEM = standard error of the mean.

a, b Means within the same column with different superscripts differ significantly (P < 0.05).

1

“–”, without E. coli O78 challenge; “+”, with E. coli O78 challenge.

2

P-values represent the main effect of the diet, the main effect of E. coli O78 challenge, and the interaction between the dietary treatments and E. coli O78 challenge.