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. 2023 Jan 5;26(2):105932. doi: 10.1016/j.isci.2023.105932

Figure 4.

Figure 4

TRT caused AKT activation by targeting PDPK1 in radioprotection in L02 cells

(A) The effect of TRT on PDPK1 mRNA after PDPK1 knockdown.

(B) The effect of TRT on PDPK1 protein after PDPK1 knockdown.

(C) The effect of TRT on AKT protein after PDPK1 knockdown.

(D) Effect of TRT on the expression of PDPK1 protein after PDPK1 knockdown and radiation injury.

(E) Influence of TRT on the expression of p-AKT protein after PDPK1 knockdown and radiation injury.

(F) Effect of TRT on the expression of PDPK1 protein after PDPK1 overexpression and radiation injury.

(G) Effect of TRT on the expression of p-AKT protein after PDPK1 overexpression and radiation injury. n = 3. ∗p < 0.01; NS: not significant. Data were shown as mean ± SEM.