TRT upregulated PDPK1 expression by targeting miR-147 during the radioprotection in the mice liver
(A) The expression of PDPK1 protein at different time points in the liver after radiation.
(B) TRT’s effect on the NEAT1 expression and PDPK1 protein expression after the radiation in pre-miR−/− mice.
(C) Effect of TRT on the expression of p-AKT and p-JNK proteins after the radiation in pre-miR−/− mice.
(D) Immunofluorescence and in situ hybridization analyses were used to detect NAET1, miR-147 and PDPK1 in irradiated liver tissues of pre-miR−/− mice pretreated with TRT. Scale bar, 20 μm n = 8. ∗p < 0.01; NS: not significant. Data were shown as mean ± SEM.