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. 2023 Jan 9;13:1093388. doi: 10.3389/fphys.2022.1093388

FIGURE 5.

FIGURE 5

Vascular preparations relaxation in response to different doses of acetylcholine against the background of norepinephrine-induced vasoconstriction of GSH-treated and untreated old rats: (A) native curves; (B) dose-dependent curves; (C) relaxation of isolated aorta rings in response to acetylcholine (1 μmol/L) in old rats, old GSH-treated and old GSH-treated rats background of L-NAME (100 μmol/L). Data are represented as mean ± SEM; n = 7–8. *р = 0.047 versus old; **р = 0.017 versus old; ***р = 0.0077 versus old; # р = 0.0026 versus old + GSH as calculated by ANOVA test.