TABLE 4.
Binary logistic regression of treatment outcomes with an adjustment for migraine subtypes, aura subtypes, number of preventive medications used and comorbidity.
| Variable | P | Exp (B) | 95% CI for Exp (B) | |
| 30% reduction from baseline of MMDs/MHDs at 3 months | ||||
| Complex aura | >0.99 | 2.009 | 0.00 | – |
| Comorbidity presence | 0.07 | 5.16 | 0.90 | 29.48 |
| Chronic migraine with/without MOH | 0.82 | 1.48 | 0.05 | 43.86 |
| Polytherapy for migraine prevention | 0.21 | 0.25 | 0.29 | 2.17 |
| History of migraine headache | 0.63 | 1.02 | 0.94 | 1.12 |
| MMDs/MHDs | 0.97 | 0.99 | 0.82 | 1.21 |
| 50% reduction from baseline of MMDs/MHDs at 3 months | ||||
| Complex aura | 0.61 | 1.95 | 0.15 | 24.93 |
| Comorbidity presence | 0.18 | 2.58 | 0.64 | 10.43 |
| Chronic migraine with/without MOH | 0.50 | 2.98 | 0.13 | 69.16 |
| Polytherapy for migraine prevention | 0.80 | 0.79 | 0.12 | 5.06 |
| History of migraine headache | 0.25 | 1.05 | 0.96 | 1.15 |
| MMDs/MHDs | 0.74 | 1.03 | 0.86 | 1.23 |
| 30% reduction from baseline of MMDs/MHDs at 6 months | ||||
| Complex aura | 0.59 | 2.75 | 0.07 | 106.38 |
| Comorbidity presence | 0.12 | 11.52 | 0.54 | 247.24 |
| Chronic migraine with/without MOH | 0.85 | 1.60 | 0.01 | 195.65 |
| Polytherapy for migraine prevention | 0.46 | 0.30 | 0.01 | 7.22 |
| History of migraine headache | 0.21 | 1.09 | 0.96 | 1.23 |
| MMDs/MHDs | 0.38 | 1.16 | 0.84 | 1.59 |
| 50% reduction from baseline of MMDs/MHDs at 6 months | ||||
| Complex aura | 0.35 | 4.75 | 0.18 | 127.39 |
| Comorbidity presence | 0.18 | 4.80 | 0.50 | 46.52 |
| Chronic migraine with/without MOH | 0.78 | 1.75 | 0.04 | 80.38 |
| Polytherapy for migraine prevention | 0.67 | 0.58 | 0.05 | 6.88 |
| History of migraine headache | 0.12 | 1.11 | 0.97 | 1.27 |
| MMDs/MHDs | 0.49 | 1.09 | 0.85 | 1.41 |
| 30% reduction from baseline of MMDs/MHDs at most recent follow-up | ||||
| Complex aura | 0.93 | 1.14 | 0.08 | 16.57 |
| Comorbidity presence | 0.51 | 1.99 | 0.26 | 15.31 |
| Chronic migraine with/without MOH | 0.09 | 1918.86 | 0.32 | 1167 |
| Polytherapy for migraine prevention | 0.55 | 0.40 | 0.02 | 8.37 |
| History of migraine headache | 0.46 | 1.04 | 0.94 | 1.16 |
| MMDs/MHDs | 0.08 | 1.54 | 0.94 | 2.50 |
| 50% reduction from baseline of MMDs/MHDs at most recent follow-up | ||||
| Complex aura | 0.62 | 1.90 | 0.15 | 23.62 |
| Comorbidity presence | 0.63 | 1.50 | 0.29 | 7.73 |
| Chronic migraine with/without MOH | 0.11 | 160.94 | 0.30 | 85897.04 |
| Polytherapy for migraine prevention | 0.96 | 1.07 | 0.07 | 16.61 |
| History of migraine headache | 0.50 | 1.03 | 0.94 | 1.14 |
| MMDs/MHDs | 0.09 | 1.34 | 0.96 | 1.89 |
MIDAS, migraine disability assessment questionnaire; MMDs/MHDs, monthly migraine/headache days; MOH, medication-overuse headache; MSQ, migraine-specific quality of life questionnaire.