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. 2023 Jan 9;9:1102420. doi: 10.3389/fmed.2022.1102420

FIGURE 1.

FIGURE 1

Proposal for disease clearance (DC) in ulcerative colitis (UC). A deep and complete UC remission achieving symptomatic remission, biological remission, mucosal healing (endoscopic and histological remission), and evolving (in future) to molecular healing with the restoration of specific molecular pathways involved in the etiopathogenesis of ulcerative colitis. PRO2, patient’s reported outcome-2; QoL, quality of life; MES, Mayo endoscopic score; FC, fecal calprotectin; NI, Nancy index; GS, Geboes score.