TABLE 3.
Docking scores of bioactive ingredients of SMW (SMW-BI) with insulin receptor substrate 1 (IRS1) and RAC-beta serine/threonine-protein kinase (AKT2).
Ligands RMSD (≤2) | Chlorogenic acid | Phellodendrine | Magnoflorine | Jateorhizine | Palmatine | Berberine | Atractydin | |
IRS1 | 1.6505 | 96.3584 | 93.3654 | 87.3707 | 96.1945 | 91.2872 | 92.0867 | 64.6741 |
AKT2 | 1.5707 | 126.0580 | 121.8040 | 93.5972 | 107.9010 | 103.7410 | 101.0050 | 75.8706 |
RMSD, root-mean-square deviation.