Table 4.
Summary of outcomes related to the effectiveness and factors evidencing the success rates (%) of regenerative endodontics as provided for the systematic reviews/meta-analyses included (n=20)
| Author | Characteristics related to effectiveness | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Follow up (months) | General success rates | General survival rates | Specific factors evidencing success of endodontic regeneration therapy | |||||||
| Min | Max | Resolution of symptoms | Apical lesion resolution | Apical closure (tooth root) | Dentin thickening | Increased tooth root length | Response to pulp sensibility tests | |||
| Pramila R [ 31 ] | 3 | 25 | -- | -- | 100.0 | 100.0 | 100.0 | 100.0 | 67.0 | -- |
| Kontakiotis EG [ 32 ] | 6 | 48 | -- | -- | 100.0 | -- | -- | -- | -- | -- |
| Antunes LS [ 33 ] | 12 | 18 | 76.0 | -- | -- | -- | -- | -- | -- | -- |
| Conde MCM [ 34 ] | 3 | 36 | 76.0 | -- | 100.0 | -- | -- | -- | -- | -- |
| Lolato A [ 35 ] | 3 | 18 | -- | -- | 100.0 | 100.0 | -- | 5.0- 15.0 | -- | Cold-Electrical: 50.0 |
| Meschi M [ 36 ] | 5 | 36 | 50.0 | -- | 76.0- 92.0 | 87.0- 95.0 | -- | -- | -- | -- |
| Ragab RA [ 37 ] | 6 | 36 | -- | -- | 100.0 | -- | -- | -- | -- | -- |
| Bucchi C [ 38 ] | 3 | 36 | -- | -- | 100.0 | 88.0 | 84.3 | 88.0 | 84.1 | -- |
| Duggal M [ 39 ] | 1 | 36 | 98.0 | -- | 40.0- 100.0 | 89.7 | -- | 20.0- 80.0 | 0.0- 100.0 | -- |
| Kahler B [ 40 ] | 3 | 36 | 89.7 | 98.6 | 100.0 | 98.0 | -- | -- | -- | -- |
| Nicoloso GF [ 41 ] | 11 | 18 | -- | 94.0 | 100.0 | 80.0- 90.0 | 100.0 | 100.0 | 100.0 | -- |
| Tong HJ [ 42 ] | 1 | 12 | 89.7 | 100.0 | 100.0 | 94.0 | BC: 76.0 PRP: 82.0 | 48.0- 70.0 | BC: 80.0 PRP: 94.0 | -- |
| Torabinejad M [ 43 ] | 6 | 36 | 91.3 | 97.1- 97.8 | 100.0 | -- | -- | -- | 79.0 | -- |
| Chisini LA [ 44 ] | 1 | 23 | 87.9 | -- | 100.0 | -- | -- | 13.0 | 8.5 | -- |
| Metlerska J [ 45 ] | 6 | 18 | -- | -- | 100.0 | 10.0- 98.0 | 20.0- 93.0 | 20.0- 93.0 | 10.0- 99.0 | Positive sensitivity: 13.3- 80.0 |
| Murray PE [ 46 ] | 3 | 25 | 76.0 | -- | -- | 89.0- 100.0 | BC: 58.8 PRF: 85.2 PRP: 85.1 |
PRP: 100.0 PRF: 100.0 BC: 100.0 |
PRP: 64.2 PRF: 74.1 BC: 64.1 |
-- |
| do Couto AM [ 47 ] | 4 | 19 | -- | -- | -- | -- | -- | -- | -- | -- |
| Nicoloso GF [ 48 ] | 8 | 35 | 89.0 | -- | 100.0 | -- | -- | -- | -- | -- |
| Rossi-Fedele G [ 49 ] | 1 | 19 | 50.0 | -- | 100.0 | 50.0 | -- | -- | -- | -- |
| Koç S [ 50 ] | 8 | 46 | 94.8 | -- | -- | -- | -- | -- | -- | -- |
PRP: Platelet-Rich Plasma, PRF: Platelet-Rich Fibrin, BC: Blood Clot