FIGURE 3.

Number of protein studies that identify a cardiovascular risk in each patient. 12 studies (Ridker et al.,⁴¹ Matsumoto et al.,²⁴ Meuwese et al.,²⁵ Morange et al.,²⁰ Canoui-Poitrine et al.,⁴⁴ Gonçalves et al.,³⁷ Wang et al.,³⁶ Herder et al.,³⁹ Pai et al.,³⁸ Doi et al.,³⁴ Herder et al.,³⁹ Persson et al.³¹) assessing the association of ten proteins (IL-6, SELE, MPO, vWF, CXCL10, CSTB, TNF-R1, NT-proBNP, IL-8 and U-PAR) with primary cardiovascular (CV) risk in non-CVD populations were included in the analysis. The CV risk threshold for each protein was calculated from its respective study in the literature, and compared with each patient’s protein levels at baseline and after treatment. The number of studies per patient that identify a protein level above a risk threshold is shown here. P1-P10 indicates patient 1—patient 10