Table 3.
Comparison of PCOS and Control glucose metabolism in non-central obesity after adjustment for body mass index and body fat percentagea.
| Glucose metabolism indicators | Non-central obesity | |||
|---|---|---|---|---|
| PCOS(n=77) | Control (n=70) | P value(Before adjustment) | P value(After adjustment) | |
| Fasting plasma glucose, (mmol/L) | 4.8 (4.6;5.5) | 5.1 (4.8;5.3) | 0.156 | 0.017 |
| Fasting insulin, (µU/ml) | 11.38 (7.95;16.4) | 6.76(4.7;10.56) | <0.001 | <0.001 |
| HOMA-IR | 2.49 (1.71;3.66) | 1.44(1.09;2.41) | <0.001 | 0.002 |
| HOMA-B | 152.91 (107.44;254.44) | 97.5 (61.25;128.64) | <0.001 | <0.001 |
| QUICKI | 0.33 (0.32;0.35) | 0.36 (0.33;0.38) | <0.001 | <0.001 |
| G/I | 0.47 (0.29;0.6) | 0.72 (0.49;1.08) | <0.001 | <0.001 |
a Variables were expressed as medians with interquartile ranges. Both the interaction term between group and body mass index (BMI) and the interaction term between group and body fat percentage(BFP) were not significant. Only the main effects of group, BMI and BFP were examined, and the p values of all regression equations were less than 0.001. HOMA-IR: homeostasis model assessment of insulin resistance; HOMA-B: homeostasis model assessment of β-cell function; QUICKI: quantitative insulin sensitivity check index; G/I: fasting glucose to insulin ratio. P-values with statistical differences (P < 0.05) have been bolded.