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. 2023 Jan 9;14:1058665. doi: 10.3389/fnagi.2022.1058665

Table 1.

Cerebrospinal fluid (CSF) sample description.

Non-AD AD with low T-Tau AD with high T-Tau Kruskal–Wallis test (p-values)
Number of subjects 8 20 20
Age range (mean ± SD) 56–81 (73 ± 7.1) 54–81 (69.9 ± 8.4) 55–81 (70.2 ± 8.4)
Sex (N) 4 M; 4 F 9 M; 11F 8 M; 12F
Onset (N) / 7 EOAD; 13 LOAD 10 EOAD; 10 LOAD
T-TAU (mean ± SD pg/ml) 258.4 ± 70.3 297.2 ± 77.7 1115.8 ± 412.1 < 0.001
p-TAU (mean ± SD pg/ml) 51.8 ± 15.2 52.1 ± 9.7 108.4 ± 35.1 < 0.001
Aβ-42 (mean ± SD pg/ml) 1037.8 ± 299.5 476.3 ± 68.8 489.1 ± 89.5 < 0.001

EOAD, early onset Alzheimer’s disease; LOAD, late onset Alzheimer’s disease.