Table 1.
IgG | 05-2N | QHN001 | QK002 | TY8-612 | TY7-501 | K1734 | K5356 | 76,107 |
---|---|---|---|---|---|---|---|---|
B | B.1.1.7 | B.1.1.7 | B.1.351 | P.1 | B.1.617.2 | B.1.617.1 | R.1 | |
WT | Alpha | Alpha | Beta | Gamma | Delta | Kappa | – | |
D043 | 11.9 | 20.3 | 18.1 | 30.7 | 10.7 | 39.7 | 31.0 | 7.0 |
D073 | 63.9 | 53.2 | 78.9 | > 100 | 58.3 | > 100 | > 100 | 42.2 |
D084 | 28.8 | 29.4 | 23.7 | 73.6 | 14.6 | 59.3 | 74.0 | 14.3 |
D091 | 54.5 | > 100 | > 100 | > 100 | 39.0 | > 100 | > 100 | 51.8 |
D197 | 16.2 | 34.6 | 27.9 | > 100 | 64.1 | 41.2 | 71.1 | 39.1 |
D202 | 74.7 | > 100 | 66.8 | > 100 | > 100 | 47.8 | 89.8 | 53.9 |
D210 | 61.3 | 65.5 | 49.3 | > 100 | 54.9 | 55.8 | 93.6 | 51.6 |
D213 | 29.5 | 26.5 | 20.2 | > 100 | 49.9 | 35.9 | 51.5 | 23.2 |
D222 | 69.5 | 54.9 | 26.3 | > 100 | 22.0 | > 100 | > 100 | 29.5 |
D245 | 22.9 | 18.5 | 10.6 | > 100 | 8.0 | 42.4 | 60.2 | 28.1 |
D251 | 30.3 | 26.2 | 16.1 | > 100 | 6.9 | 29.1 | 52.6 | 23.0 |
D310 | 28.4 | 17.2 | 15.0 | 59.2 | 9.3 | 36.7 | 61.7 | 28.9 |
D067 | 81.5 | 64.2 | > 100 | > 100 | 85.2 | 42.0 | 47.2 | 25.6 |
D291 | 36.0 | 28.6 | 48.7 | > 100 | 59.8 | 42.8 | 40.0 | 19.3 |
D293 | 63.8 | 40.2 | 70.9 | > 100 | 87.8 | 59.7 | > 100 | 29.8 |
D242 | 44.7 | 64.4 | 61.3 | > 100 | 21.7 | 58.6 | 56.1 | 24.6 |
D260 | 19.2 | 13.6 | 7.5 | 18.6 | < 6.3 | 52.2 | 55.4 | < 6.3 |
D351 | 40.2 | 32.2 | 22.1 | > 100 | 17.0 | 49.7 | 84.7 | 22.0 |
D379 | 78.3 | > 100 | 62.5 | 67.8 | 53.0 | 29.2 | 34.2 | 14.4 |
D384 | 20.0 | 36.3 | 27.4 | 85.9 | 12.7 | 30.3 | 47.8 | 20.3 |
D393 | 43.6 | 64.1 | 54.9 | > 100 | 23.6 | 26.3 | 57.9 | 17.3 |
D394 | 46.7 | 47.2 | 63.7 | > 100 | 46.3 | 42.6 | > 100 | 41.2 |
D318 | 10.4 | 27.7 | 28.0 | 75.9 | 9.5 | 26.1 | 40.6 | 12.0 |
D373 | 19.9 | 51.9 | 66.0 | > 100 | 20.0 | 18.0 | 34.5 | 15.5 |
D375 | 17.1 | 33.2 | 39.0 | 78.5 | 18.1 | 25.3 | > 100 | 21.3 |
D408 | 19.0 | 58.6 | 56.7 | 90.8 | 22.1 | 26.8 | 38.5 | 13.9 |
D390 | 27.6 | 53.2 | 41.6 | > 100 | 41.0 | 27.9 | 42.9 | 25.8 |
D409 | 7.6 | 13.6 | 10.1 | 17.1 | < 6.3 | 42.7 | 63.7 | 8.1 |
D410 | 13.6 | 22.1 | 16.0 | 52.1 | 10.2 | 20.3 | 36.5 | 9.1 |
D456 | < 6.3 | 13.0 | 16.9 | 35.7 | 7.4 | 15.9 | 30.3 | < 6.3 |
mAb1414 | 0.72 | > 10 | NT | > 10 | > 10 | > 10 | > 10 | 5.12 |
mAb2414 | 5.78 | > 10 | NT | > 10 | 3.46 | > 10 | > 10 | > 10 |
mAb40591 | 3.27 | 5.46 | NT | > 10 | 0.88 | 2.62 | > 10 | 1.35 |
pAbA19215 | < 0.63 | < 0.63 | NT | > 10 | > 10 | < 0.63 | 5.56 | < 0.63 |
Data are IC50 (µg/ml) values.