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. 2023 Jan 23;13:1263. doi: 10.1038/s41598-023-28591-3

Table 1.

Convalescent plasma antiviral activity of IgGs in VeroE6TMPRSS2.

IgG 05-2N QHN001 QK002 TY8-612 TY7-501 K1734 K5356 76,107
B B.1.1.7 B.1.1.7 B.1.351 P.1 B.1.617.2 B.1.617.1 R.1
WT Alpha Alpha Beta Gamma Delta Kappa
D043 11.9 20.3 18.1 30.7 10.7 39.7 31.0 7.0
D073 63.9 53.2 78.9  > 100 58.3  > 100  > 100 42.2
D084 28.8 29.4 23.7 73.6 14.6 59.3 74.0 14.3
D091 54.5  > 100  > 100  > 100 39.0  > 100  > 100 51.8
D197 16.2 34.6 27.9  > 100 64.1 41.2 71.1 39.1
D202 74.7  > 100 66.8  > 100  > 100 47.8 89.8 53.9
D210 61.3 65.5 49.3  > 100 54.9 55.8 93.6 51.6
D213 29.5 26.5 20.2  > 100 49.9 35.9 51.5 23.2
D222 69.5 54.9 26.3  > 100 22.0  > 100  > 100 29.5
D245 22.9 18.5 10.6  > 100 8.0 42.4 60.2 28.1
D251 30.3 26.2 16.1  > 100 6.9 29.1 52.6 23.0
D310 28.4 17.2 15.0 59.2 9.3 36.7 61.7 28.9
D067 81.5 64.2  > 100  > 100 85.2 42.0 47.2 25.6
D291 36.0 28.6 48.7  > 100 59.8 42.8 40.0 19.3
D293 63.8 40.2 70.9  > 100 87.8 59.7  > 100 29.8
D242 44.7 64.4 61.3  > 100 21.7 58.6 56.1 24.6
D260 19.2 13.6 7.5 18.6  < 6.3 52.2 55.4  < 6.3
D351 40.2 32.2 22.1  > 100 17.0 49.7 84.7 22.0
D379 78.3  > 100 62.5 67.8 53.0 29.2 34.2 14.4
D384 20.0 36.3 27.4 85.9 12.7 30.3 47.8 20.3
D393 43.6 64.1 54.9  > 100 23.6 26.3 57.9 17.3
D394 46.7 47.2 63.7  > 100 46.3 42.6  > 100 41.2
D318 10.4 27.7 28.0 75.9 9.5 26.1 40.6 12.0
D373 19.9 51.9 66.0  > 100 20.0 18.0 34.5 15.5
D375 17.1 33.2 39.0 78.5 18.1 25.3  > 100 21.3
D408 19.0 58.6 56.7 90.8 22.1 26.8 38.5 13.9
D390 27.6 53.2 41.6  > 100 41.0 27.9 42.9 25.8
D409 7.6 13.6 10.1 17.1  < 6.3 42.7 63.7 8.1
D410 13.6 22.1 16.0 52.1 10.2 20.3 36.5 9.1
D456  < 6.3 13.0 16.9 35.7 7.4 15.9 30.3  < 6.3
mAb1414 0.72  > 10 NT  > 10  > 10  > 10  > 10 5.12
mAb2414 5.78  > 10 NT  > 10 3.46  > 10  > 10  > 10
mAb40591 3.27 5.46 NT  > 10 0.88 2.62  > 10 1.35
pAbA19215  < 0.63  < 0.63 NT  > 10  > 10  < 0.63 5.56  < 0.63

Data are IC50 (µg/ml) values.