(A) HPK
proliferation on interfaces conditioned with different
supercharged albumins, functionalized with ECM proteins and assembled
with or without co-surfactant PFBC. (B) Selected images of cells spreading
at corresponding liquid–liquid interfaces after 3 and 7 days
of culture at TCP, cBSA/FN, and aBSA/Col I with PFBC. Images are corresponding
nuclear stainings. Scale bars are 200 μm. (C) Quantification
of HPK spreading area (24 h after seeding) characterized on pinned
droplets functionalized with corresponding nanosheets. (D) Quantification
of laminin deposition at liquid–liquid interfaces. (E) Bright-field
and confocal images of HPKs cultured for 7 days on emulsions stabilized
by protein nanosheets (blue, DAPI; red, phalloidin; green, vinculin;
and purple, laminin). Scale bars are 100 μm (bright-field) and
50 μm (confocal). Error bars are s.e.m.; n =
3.